PSMG4 - proteasome assembly chaperone 4 Gene

Also Known as PAC4; C6orf86; bA506K6.2

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 389362

About PSMG4

Cytogenetic location: 6p25.2 Genomic coordinates (GRCh38): 6:3,254,404-3,268,049 (from NCBI)

This gene has 10 transcripts (splice variants) and 113 orthologues. Ubiquitous expression in thyroid (RPKM 1.1), prostate (RPKM 1.0) and 25 other tissues.

Summary

Predicted to be involved in Proteasome assembly. Predicted to be part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

PSMG4 Products (3)

mRNA	Protein	Name
NM_001128591.2	NP_001122063.1	proteasome assembly chaperone 4 isoform b
NM_001128592.2	NP_001122064.1	proteasome assembly chaperone 4 isoform a
NM_001135750.2	NP_001129222.1	proteasome assembly chaperone 4 isoform c

Protein Preferred Names	Protein Names
proteasome assembly chaperone 4	PAC-4

Related Diseases

Diseases	Alias
Neuropathy, Hereditary Sensory And Autonomic, Type Vi	Hereditary Sensory And Autonomic Neuropathy Type 6 HSAN6 Hsan Vi Hereditary Sensory And Autonomic Neuropathy Type Vi Familial Dysautonomia With Contractures Neuropathy, Hereditary Sensory And Autonomic, 6 Hereditary Sensory Neuropathy Type Vi Hsn Vi Neuropathy, Sensory And Autonomic, Hereditary, Type Vi
Robinow Syndrome, Autosomal Dominant 1	Autosomal Dominant Robinow Syndrome 1 DRS1 Robinow Dwarfism Fetal Face Syndrome Acral Dysostosis With Facial And Genital Abnormalities Robinow, Autosomal Dominant Syndrome, Type 1
Neuropathy, Hereditary Motor And Sensory, Russe Type	Charcot-Marie-Tooth Disease Type 4g HMSNR Cmt4g Hereditary Motor And Sensory Neuropathy, Russe Type Charcot-Marie-Tooth Disease, Type 4g Charcot-Marie-Tooth Disease, Autosomal Recessive, Type 4g Charcot-Marie-Tooth Neuropathy Type 4g Charcot-Marie-Tooth Neuropathy, Type 4g Autosomal Recessive Charcot-Marie-Tooth Disease Type 4g Hereditary Motor And Sensory Neuropathy Russe Type Charcot-Marie-Tooth Disease Autosomal Recessive Type 4g
Nodular Nonsuppurative Panniculitis	Weber-Christian Disease Relapsing Febrile Nodular Nonsuppurative Panniculitis Idiopathic Nodular Panniculitis Pfeiffer-Weber-Christian Syndrome Weber-Christian Panniculitis Panniculitis, Nodular Nonsuppurative Nodular Non-Suppurative Febrile Panniculitis Weber - Christian Disease Panniculitis Nodular Nonsuppurative Nodular Non-Suppurative Panniculitis Idiopathic Lobular Panniculitis Relapsing Febrile Nodular Panniculitis Wcd

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11339	PSMG4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PSMG4	RGD	RGD:1589955
Mus musculus	PSMG4	MGD	MGI:1916916
Bos taurus	PSMG4	VGNC	VGNC:33481
Macaca mulatta	PSMG4	VGNC	VGNC:76296
Others	PSMG4	NCBI