Sucnr1 - succinate receptor 1 Gene

Also Known as Gpr91

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 408199

About Sucnr1

Primary_assembly 2: 144,219,122-144,230,034 forward strand.mRatBN7.2:CM026975.1

This gene has 1 transcript (splice variant), 211 orthologues and 13 paralogues.

Summary

Predicted to enable signaling receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within several processes, including macrophage activation involved in immune response; regulation of angiotensin metabolic process; and Renin secretion into blood stream. Predicted to be integral component of membrane. Orthologous to human SUCNR1 (Succinate Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Sucnr1 Products (1)

mRNA Protein Name
NM_001001518.2 NP_001001518.1 succinate receptor 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled receptor activity IDA
IDA: Inferred from direct assay
18836459 RGD
Biological Process GO Annotation Evidence References Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
18836459 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Sucnr1 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (19 - 300)

7tm_GPCRs

7tm_GPCRs: cd14964 (21 - 45)

7tm_GPCRs

7tm_GPCRs: cd14964 (54 - 75)

7tm_GPCRs

7tm_GPCRs: cd14964 (91 - 113)

7tm_GPCRs

7tm_GPCRs: cd14964 (136 - 152)

7tm_GPCRs

7tm_GPCRs: cd14964 (180 - 203)

7tm_GPCRs

7tm_GPCRs: cd14964 (226 - 248)

7tm_GPCRs

7tm_GPCRs: cd14964 (268 - 293)

  • 0
  • 100
  • 200
  • 300
  • 317 a.a.
Protein Preferred Names Protein Names

succinate receptor 1

  • G-protein coupled receptor 91

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-130246 NF-56-EJ40 99.88% Unkown
HY-125791 cis-Epoxysuccinic acid Agonist 98.0% Unkown
HY-150205 Succinate/succinate receptor antagonist 1 Antagonist 99.40% Unkown
HY-154946 SUCNR1-IN-1 Inhibitor 99.39% Unkown
HY-156955 SUCNR1-IN-2 Inhibitor 99.74% Unkown
HY-RS14004 Sucnr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-130246A NF-56-EJ40 hydrochloride 98.45% Unkown
HY-N1910 4'-O-Methylbavachalcone Inhibitor 99.64% Unkown
HY-RS14003 SUCNR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-183639 SUCNR1 antagonist-1 / Unkown
HY-RS14005 Sucnr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sucnr1 NCBI NCBI:56670