CCR2 - C-C motif chemokine receptor 2 Gene

Canis lupus familiaris (sub-species: familiaris)

Gene ID: 484790 | Gene type: protein coding

About CCR2

Primary_assembly 20: 42,787,205-42,793,246 reverse strand.ROS_Cfam_1.0:CM025119.1

This gene has 1 transcript (splice variant), 151 orthologues and 22 paralogues.

CCR2 Products(3)

mRNA	Protein	Name
XM_038427985.1	XP_038283913.1	C-C chemokine receptor type 2
XM_038427986.1	XP_038283914.1	C-C chemokine receptor type 2
XM_038427987.1	XP_038283915.1	C-C chemokine receptor type 2

CCR2 Protein Structure

7tm_GPCRs

0
100
200
300
372 a.a.

Protein Preferred Names

Protein Names

C-C chemokine receptor type 2

chemokine (C-C motif) receptor 2

Related Agents

Approval

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B1076	Medrysone	Activator	99.79%	Unkown
HY-117621A	PF-04634817 succinate	Antagonist	99.50%	Unkown
HY-117621	PF-04634817	Antagonist	98.87%	Unkown

Clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Phase
HY-14882	Cenicriviroc	Antagonist	99.51%	Phase 3
HY-14882A	Cenicriviroc Mesylate	Antagonist	99.94%	Phase 3
HY-13245	PF-4136309	Antagonist	99.86%	Phase 2
HY-109593	BMS-813160	Antagonist	99.93%	Phase 2
HY-101713	Ilacirnon	Inhibitor	98.05%	Phase 2
HY-50669A	MK-0812 Succinate	Antagonist	99.94%	Phase 2

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99781	Plozalizumab	Inhibitor	99.53%	Phase 2

Pre-clinical Phase

Bioactive Molecules (41)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15418	RS 504393	Antagonist	99.72%	Unkown
HY-50674	INCB3344	Antagonist	99.08%	Unkown
HY-13406	TAK-779	Antagonist	99.89%	Unkown
HY-18611A	Abaucin	Antagonist	99.59%	Unkown
HY-18611	Abaucin hydrochloride	Antagonist	99.90%	Unkown
HY-108323	CCR2 antagonist 4	Antagonist	99.89%	Unkown
HY-50081	CCR2-RA-[R]	Antagonist	99.21%	Unkown
HY-15450A	INCB 3284	Antagonist	99.30%	Unkown
HY-103362	CCR2 antagonist 4 hydrochloride	Antagonist	99.91%	Unkown
HY-101908	BMS CCR2 22	Antagonist	99.27%	Unkown
HY-103355	YM022	Antagonist	99.87%	Unkown
HY-50669	MK-0812	Antagonist	99.89%	Yes
HY-135891	AZD2423	Antagonist	99.91%	Unkown
HY-402739	CCR2-IN-1	Inhibitor	/	Unkown
HY-13499	JNJ-41443532	Inhibitor	99.65%	Unkown
HY-101264	CCR2 antagonist 3	Antagonist	99.91%	Unkown
HY-110132	JNJ-27141491	Antagonist	97.01%	Unkown
HY-112792	CCR2 antagonist 1	Antagonist	98.00%	Unkown
HY-50674A	INCB3344 R-isomer		98.01%	Unkown
HY-P11553B	DOTA-ECL1i	Inhibitor	98.06%	Unkown
HY-15450	INCB 3284 dimesylate	Antagonist	≥98.0%	Unkown
HY-100819	RO5234444	Antagonist	/	Unkown
HY-P11553	ECL1i	Inhibitor	/	Unkown
HY-171685	Anti-CCL2 (Carlumab)-MC-Vc-PAB-DMEA-PEG2-Duocarmycin SA	Antagonist	/	Unkown
HY-136768	YJC-10592	Antagonist	/	Unkown
HY-181681	CXCR2 antagonist 10	Antagonist	/	Unkown
HY-171682	Anti-CCL2 (Carlumab)-McMMAF	Antagonist	/	Unkown
HY-180572	CCR2 ligand-1	Ligand	/	Unkown
HY-171681	Anti-CCL2 (Carlumab)-SPDB-DM4	Antagonist	/	Unkown
HY-171680	Anti-CCL2 (Carlumab)-SMCC-DM1	Antagonist	/	Unkown
HY-N17908	Viscumneoside V	Inhibitor	98.24%	Unkown
HY-179607	LUF8100	Antagonist	98.64%	Unkown
HY-50084	CCR2-RA	Antagonist	/	Unkown
HY-129991	JNJ-17166864	Antagonist	/	Unkown
HY-180571	LUF7996	Degrader	/	Unkown
HY-171684	Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38	Antagonist	/	Unkown
HY-119658	PF-4178903	Antagonist	/	Unkown
HY-19009B	Propagermanium	Inhibitor	/	Unkown
HY-108432	BMS-741672	Antagonist	/	Unkown
HY-185299	CCR2 antagonist 6	Antagonist	/	Unkown
HY-148100C	Emapticap pegol scramble negative control	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	CCR2	NCBI	NCBI:729230
Mus musculus	CCR2	NCBI	NCBI:12772

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