CCR2 - C-C motif chemokine receptor 2 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 484790

About CCR2

Primary_assembly 20: 42,787,205-42,793,246 reverse strand.ROS_Cfam_1.0:CM025119.1

This gene has 1 transcript (splice variant), 151 orthologues and 22 paralogues.

CCR2 Products (3)

mRNA Protein Name
XM_038427985.1 XP_038283913.1 C-C chemokine receptor type 2
XM_038427986.1 XP_038283914.1 C-C chemokine receptor type 2
XM_038427987.1 XP_038283915.1 C-C chemokine receptor type 2

CCR2 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (55 - 327)

7tm_GPCRs

7tm_GPCRs: cd14964 (56 - 80)

7tm_GPCRs

7tm_GPCRs: cd14964 (89 - 110)

7tm_GPCRs

7tm_GPCRs: cd14964 (125 - 147)

7tm_GPCRs

7tm_GPCRs: cd14964 (170 - 186)

7tm_GPCRs

7tm_GPCRs: cd14964 (211 - 234)

7tm_GPCRs

7tm_GPCRs: cd14964 (253 - 275)

7tm_GPCRs

7tm_GPCRs: cd14964 (295 - 320)

  • 0
  • 100
  • 200
  • 300
  • 372 a.a.
Protein Preferred Names Protein Names

C-C chemokine receptor type 2

  • chemokine (C-C motif) receptor 2

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1076 Medrysone Activator 99.79% Unkown
HY-117621A PF-04634817 succinate Antagonist 99.50% Unkown
HY-117621 PF-04634817 Antagonist 98.87% Unkown

Clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Phase
HY-14882 Cenicriviroc Antagonist 99.51% Phase 3
HY-14882A Cenicriviroc Mesylate Antagonist 99.94% Phase 3
HY-13245 PF-4136309 Antagonist 99.86% Phase 2
HY-109593 BMS-813160 Antagonist 99.93% Phase 2
HY-101713 Ilacirnon Inhibitor 98.05% Phase 2
HY-50669A MK-0812 Succinate Antagonist 99.94% Phase 2
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99781 Plozalizumab Inhibitor 99.53% Phase 2

Pre-clinical Phase

Bioactive Molecules (41)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15418 RS 504393 Antagonist 99.72% Unkown
HY-50674 INCB3344 Antagonist 99.81% Unkown
HY-13406 TAK-779 Antagonist 99.89% Unkown
HY-18611A Abaucin Antagonist 99.59% Unkown
HY-18611 Abaucin hydrochloride Antagonist 99.94% Unkown
HY-108323 CCR2 antagonist 4 Antagonist 99.89% Unkown
HY-50081 CCR2-RA-[R] Antagonist 99.21% Unkown
HY-103355 YM022 Antagonist 99.87% Unkown
HY-15450A INCB 3284 Antagonist 99.30% Unkown
HY-103362 CCR2 antagonist 4 hydrochloride Antagonist 99.91% Unkown
HY-101908 BMS CCR2 22 Antagonist 99.27% Unkown
HY-50669 MK-0812 Antagonist 99.89% Yes
HY-135891 AZD2423 Antagonist 99.91% Unkown
HY-101264 CCR2 antagonist 3 Antagonist 99.91% Unkown
HY-402739 CCR2-IN-1 Inhibitor / Unkown
HY-13499 JNJ-41443532 Inhibitor 99.65% Unkown
HY-110132 JNJ-27141491 Antagonist 97.01% Unkown
HY-112792 CCR2 antagonist 1 Antagonist 95.04% Unkown
HY-50674A INCB3344 R-isomer 98.01% Unkown
HY-P11553B DOTA-ECL1i Inhibitor 98.06% Unkown
HY-15450 INCB 3284 dimesylate Antagonist ≥98.0% Unkown
HY-100819 RO5234444 Antagonist / Unkown
HY-P11553 ECL1i Inhibitor / Unkown
HY-171685 Anti-CCL2 (Carlumab)-MC-Vc-PAB-DMEA-PEG2-Duocarmycin SA Antagonist / Unkown
HY-136768 YJC-10592 Antagonist / Unkown
HY-181681 CXCR2 antagonist 10 Antagonist / Unkown
HY-171682 Anti-CCL2 (Carlumab)-McMMAF Antagonist / Unkown
HY-180572 CCR2 ligand-1 Ligand / Unkown
HY-171681 Anti-CCL2 (Carlumab)-SPDB-DM4 Antagonist / Unkown
HY-171680 Anti-CCL2 (Carlumab)-SMCC-DM1 Antagonist / Unkown
HY-N17908 Viscumneoside V Inhibitor 98.24% Unkown
HY-179607 LUF8100 Antagonist 98.64% Unkown
HY-50084 CCR2-RA Antagonist / Unkown
HY-129991 JNJ-17166864 Antagonist / Unkown
HY-180571 LUF7996 Degrader / Unkown
HY-171684 Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38 Antagonist / Unkown
HY-119658 PF-4178903 Antagonist / Unkown
HY-19009B Propagermanium Inhibitor / Unkown
HY-108432 BMS-741672 Antagonist / Unkown
HY-185299 CCR2 antagonist 6 Antagonist / Unkown
HY-148100C Emapticap pegol scramble negative control Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CCR2 NCBI NCBI:729230