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INCB3344 R-isomer 

Cat. No.: HY-50674A Purity: 96.58%
Handling Instructions

INCB3344 R-isomer is the R-isomer of INCB3344. INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.

For research use only. We do not sell to patients.

INCB3344 R-isomer Chemical Structure

INCB3344 R-isomer Chemical Structure

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 496 In-stock
Estimated Time of Arrival: December 31
5 mg USD 390 In-stock
Estimated Time of Arrival: December 31
10 mg USD 590 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1900 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of INCB3344 R-isomer:

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Description

INCB3344 R-isomer is the R-isomer of INCB3344. INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity[1].

Molecular Weight

577.59

Formula

C₂₉H₃₄F₃N₃O₆

SMILES

CCO[[email protected]]1CN([[email protected]]2([H])CC[[email protected]](C3=CC(OCO4)=C4C=C3)(O)CC2)C[[email protected]@H]1NC(CNC(C5=CC(C(F)(F)F)=CC=C5)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 106.5 mg/mL (184.39 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7313 mL 8.6567 mL 17.3133 mL
5 mM 0.3463 mL 1.7313 mL 3.4627 mL
10 mM 0.1731 mL 0.8657 mL 1.7313 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

INCB3344 R-isomerOthersInhibitorinhibitorinhibit

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INCB3344 R-isomer
Cat. No.:
HY-50674A
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