2. Antibody-drug Conjugate/ADC Related Immunology/Inflammation GPCR/G Protein Cell Cycle/DNA Damage
  3. Antibody-Drug Conjugates (ADCs) CCR Topoisomerase
  4. Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38

Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38 is an antibody-drug conjugate (ADC) consisting of the humanized anti-CCL2 (chemokine ligand 2) antibody Carlumab (HY-P99188) conjugated to the linker Mc-VC-PAB and the topoisomerase I inhibitor SN38 (HY-13704). The ADC toxic molecule and linker part are Mc-VC-PAB-SN38 (HY-131057). Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38 can be used in cancer research.

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Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38

Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38 Chemical Structure

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Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38 Related Antibodies

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Voir tous les produits spécifiques à Isoform CCR:

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CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9

Voir tous les produits spécifiques à Isoform Topoisomerase:

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Topoisomerase Topo I Topo II DNA gyrase

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Description

Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38 is an antibody-drug conjugate (ADC) consisting of the humanized anti-CCL2 (chemokine ligand 2) antibody Carlumab (HY-P99188) conjugated to the linker Mc-VC-PAB and the topoisomerase I inhibitor SN38 (HY-13704). The ADC toxic molecule and linker part are Mc-VC-PAB-SN38 (HY-131057). Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38 can be used in cancer research[1][2].

IC50 & Target[1][2]

CCR2

 

Topoisomerase I

 

SMILES

[Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38]
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38Antibody-Drug Conjugates (ADCs)CCRTopoisomeraseAntibody-Drug ConjugatesCC chemokine receptorADCanticancerInhibitorinhibitorinhibit

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Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38
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