Copy Link Print Information

Carlumab

(Synonyms: CNTO 888)
4 Cited Publications
Customer Review

Based on 4 publication(s) in Google Scholar

Carlumab (CNTO 888) is a human anti-CCL2 (chemokine ligand 2) monoclonal antibody. Carlumab binds and neutralises profibrotic activities of human CCL2. Carlumab inhibits tumor growth by reducing macrophage infiltration and decreasing tumor microvascular density. Carlumab can be used for the research of cancer, suah as prostate cancer.

For research use only. We do not sell to patients.

  • Purity: 97.80%
  • CAS No.: 915404-94-3
  • Molecular Weight:144.87 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Carlumab
  • Experimental Validation Results for Carlumab
  • Experimental Validation Results for Carlumab
  • Carlumab Chemical Structure
    Carlumab Chemical Structure
CAS No.: 915404-94-3
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Carlumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Carlumab

More

All CCR Isoforms

More
Keywords
MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized MCP-1/CCL2 Protein, Human (HY-P7237) can bind Carlumab. The EC50 for this effect is 9.459 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5X106 RAW264.7 cells treated with 100ng/mL LPS for 4 hours add 1μg/mL BFA for3 hours with Carlumab (HY-P99188, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃, Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control，cells without incubation with primary antibody were used as the unlabeled control (black).

  • Carlumab Chemical Structure
    1/16
  • Carlumab
  • Immobilized MCP-1/CCL2 Protein, Human (HY-P7237) can bind Carlumab. The EC50 for this effect is 9.459 ng/mL.
  • Flow cytometric analysis of 1.5X106 RAW264.7 cells treated with 100ng/mL LPS for 4 hours add 1μg/mL BFA for3 hours with Carlumab (HY-P99188, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃, Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control，cells without incubation with primary antibody were used as the unlabeled control (black).