HEBP1 - heme binding protein 1 Gene

Also Known as HBP; HEBP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 50865

About HEBP1

Cytogenetic location: 12p13.1 Genomic coordinates (GRCh38): 12:12,974,870-13,000,265 (from NCBI)

This gene has 5 transcripts (splice variants), 148 orthologues and 1 paralogue. Ubiquitous expression in duodenum (RPKM 103.7), small intestine (RPKM 72.8) and 25 other tissues.

Summary

The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 Amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells. [provided by RefSeq, Jul 2008]

HEBP1 Products (1)

mRNA Protein Name
NM_015987.5 NP_057071.2 heme-binding protein 1

HEBP1 Protein Structure

SOUL

SOUL: SOUL heme-binding protein (13 - 186)

  • 0
  • 100
  • 189 a.a.
Protein Preferred Names Protein Names

heme-binding protein 1

  • p22HBP

Related Diseases

Diseases Alias
Pica Disease

  • Pica
Proliferative Vasculopathy And Hydranencephaly-Hydrocephaly Syndrome

  • Fowler Syndrome

  • Encephaloclastic Proliferative Vasculopathy

  • Hydrocephaly/Hydranencephaly Due To Cerebral Vasculopathy

  • PVHH

  • Epv

  • Cerebral Proliferative Glomeruloid Vasculopathy

  • Hydranencephaly, Fowler Type

  • Proliferative Vasculopathy And Hydranencephaly/Hydrocephaly

  • Fowler'S Syndrome

  • Fowler Christmas Chapple Syndrome

  • Fowler Vasculopathy

  • Polycystic Ovaries Urethral Sphincter Dysfunction

  • Voiding Dysfunction And Polycystic Ovaries

  • Fowler Vasculopaty

  • Hydranencephaly Fowler Type

  • Pgv

  • Polycystic Ovaries-Urethral Sphincter Dysfunction Syndrome
Folate Malabsorption, Hereditary

  • Hereditary Folate Malabsorption

  • Congenital Defect Of Folate Absorption

  • Congenital Folate Malabsorption

  • Folic Acid Transport Defect

  • HFM
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09245 NFE2L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06104 HEBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18823 Hebp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25313 Hebp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus HEBP1 RGD RGD:1304581
Mus musculus HEBP1 MGD MGI:1333880
Macaca mulatta HEBP1 VGNC VGNC:73184
Felis catus HEBP1 VGNC VGNC:62781
Canis familiaris HEBP1 VGNC VGNC:41639
Others HEBP1 NCBI