PI15 - peptidase inhibitor 15 Gene

Also Known as P24TI; P25TI; CRISP8

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51050

About PI15

Cytogenetic location: 8q21.13 Genomic coordinates (GRCh38): 8:74,824,534-74,855,029 (from NCBI)

This gene has 3 transcripts (splice variants), 275 orthologues and 13 paralogues. Biased expression in appendix (RPKM 36.9), prostate (RPKM 13.1) and 3 other tissues.

Summary

This gene encodes a trypsin inhibitor. The protein shares similarity to insect venom allergens, mammalian testis-specific proteins and plant pathogenesis-related proteins. It is frequently expressed in human neuroblastoma and glioblastoma cell lines, and thus may play a role in the central nervous system. [provided by RefSeq, Jul 2008]

PI15 Products (2)

mRNA Protein Name
NM_001324403.2 NP_001311332.1 peptidase inhibitor 15 preproprotein
NM_015886.5 NP_056970.1 peptidase inhibitor 15 preproprotein

PI15 Protein Structure

CAP

CAP: Cysteine-rich secretory protein family (71 - 211)

  • 0
  • 100
  • 200
  • 258 a.a.
Protein Preferred Names Protein Names

peptidase inhibitor 15

  • 25 kDa trypsin inhibitor

Related Diseases

Diseases Alias
Neuroblastoma

  • Nb

  • Neuroblastoma, Susceptibility To

  • Neuroblastomas

  • Central Neuroblastoma
Corneal Dystrophy, Meesmann, 1

  • Meesmann Corneal Dystrophy

  • Mecd

  • Corneal Dystrophy, Meesmann Epithelial

  • Juvenile Hereditary Epithelial Dystrophy

  • Corneal Dystrophy, Juvenile Epithelial Of Meesmann

  • MECD1

  • Meesmann Corneal Dystrophy 1

  • Meesmann Corneal Epithelial Dystrophy

  • Meesmann Epithelial Corneal Dystrophy

  • Corneal Dystrophy, Juvenile Epithelial, Of Meesmann

  • Stocker-Holt Dystrophy

  • Meesman Dystrophy

  • Meesman'S Corneal Dystrophy

  • Juvenile Hereditary Epithelial Dystrophy Of Meesmann

  • Corneal Dystrophy, Meesmann 1

  • Juvenile Epithelial Corneal Dystrophy Of Meesmann

  • Mcd

  • Dystrophy, Corneal, Meesmann
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-172802 TrkA-IN-10 Inhibitor / Unkown
HY-RS10461 PI15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PI15 RGD RGD:1309577
Mus musculus PI15 MGD MGI:1934659
Macaca mulatta PI15 VGNC VGNC:81496
Canis familiaris PI15 VGNC VGNC:44514
Bos taurus PI15 VGNC VGNC:32852
Others PI15 NCBI