BET1L - Bet1 golgi vesicular membrane trafficking protein like Gene

Also Known as GS15; BET1L1; GOLIM3; HSPC197

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51272

About BET1L

Cytogenetic location: 11p15.5 Genomic coordinates (GRCh38): 11:202,924-207,399 (from NCBI)

This gene has 7 transcripts (splice variants) and 185 orthologues. Ubiquitous expression in ovary (RPKM 28.0), thyroid (RPKM 22.6) and 25 other tissues.

Summary

Enables SNAP receptor activity. Involved in regulation of retrograde vesicle-mediated transport, Golgi to ER and retrograde transport, endosome to Golgi. Located in Golgi apparatus and endosome. Implicated in uterine fibroid. Biomarker of endometrial adenocarcinoma. [provided by Alliance of Genome Resources, Apr 2022]

BET1L Products (2)

mRNA Protein Name
NM_001098787.2 NP_001092257.1 BET1-like protein isoform 1
NM_016526.5 NP_057610.2 BET1-like protein isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables SNAP receptor activity IDA
IDA: Inferred from direct assay
15215310 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
34711829 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in regulation of retrograde vesicle-mediated transport, Golgi to ER IMP
IMP: Inferred from mutant phenotype
17389686 GOA
involved in retrograde transport, endosome to Golgi IDA
IDA: Inferred from direct assay
15215310 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
15215310 GOA
located in endosome IDA
IDA: Inferred from direct assay
15215310 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BET1L Protein Structure

SNARE

SNARE: SNARE domain (20 - 80)

  • 0
  • 100
  • 111 a.a.
Protein Preferred Names Protein Names

BET1-like protein

  • GOS-15

Related Diseases

Diseases Alias
Endometrial Adenocarcinoma

  • Endometrial Endometrioid Adenocarcinoma

  • Endometrial Adenoacanthoma

  • Endometrial Endometrioid Adenocarcinoma, Variant With Squamous Differentiation

  • Adenocarcinoma Of Endometrium

  • Adenocarcinoma Of The Endometrium

  • Adenocarcinoma Of Uterus

  • Endometrial Endometrioid Adenocarcinoma With Squamous Differentiation

  • Endometrioid Adenoma Or Carcinoma

  • Endometrioid Adenomas And Carcinomas

  • Endometrioid Carcinoma Of Endometrium

  • Endometrium Adenocarcinoma
Uterine Benign Neoplasm
Reproductive Organ Benign Neoplasm
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS01479 BET1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus BET1L VGNC VGNC:60105
Macaca mulatta BET1L VGNC VGNC:70347
Canis familiaris BET1L VGNC VGNC:38438
Rattus norvegicus BET1L RGD RGD:71051
Bos taurus BET1L VGNC VGNC:26476
Mus musculus BET1L MGD MGI:1913128
Others BET1L NCBI