FKBP11 - FKBP prolyl isomerase 11 Gene

Also Known as FKBP19

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51303

About FKBP11

Cytogenetic location: 12q13.12 Genomic coordinates (GRCh38): 12:48,921,963-48,939,034 (from NCBI)

This gene has 13 transcripts (splice variants), 199 orthologues and 18 paralogues. Ubiquitous expression in pancreas (RPKM 27.0), appendix (RPKM 17.8) and 24 other tissues.

Summary

FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al., 2006 [PubMed 16596453]).[supplied by OMIM, Mar 2008]

FKBP11 Products (3)

mRNA Protein Name
NM_001143781.2 NP_001137253.1 peptidyl-prolyl cis-trans isomerase FKBP11 isoform 2
NM_001143782.2 NP_001137254.1 peptidyl-prolyl cis-trans isomerase FKBP11 isoform 3 precursor
NM_016594.3 NP_057678.1 peptidyl-prolyl cis-trans isomerase FKBP11 isoform 1 precursor

FKBP11 Protein Structure

FKBP_C

FKBP_C: FKBP-type peptidyl-prolyl cis-trans isomerase (54 - 141)

  • 0
  • 100
  • 201 a.a.
Protein Preferred Names Protein Names

peptidyl-prolyl cis-trans isomerase FKBP11

  • 19 kDa FK506-binding protein

Recombinant FKBP11 Proteins

Cat. No. Product Name Accession Purity
HY-P76344 FKBP11 Protein, Human (HEK293, Fc) Q9NYL4 (G28-G155) ≥ 90%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Osteogenesis Imperfecta, Type V

  • Osteogenesis Imperfecta Type 5

  • OI5

  • Osteogenesis Imperfecta Type V

  • Oi Type 5

  • Oi Type V

  • Oi, Type V

  • Oi With Calcification In Interosseous Membranes

  • Type V Oi

  • Osteogenesis Imperfecta 5

  • Oi-V
Caffey Disease

  • Infantile Cortical Hyperostosis

  • CAFYD

  • Cortical Congenital Hyperostosis

  • Caffey-Silverman Syndrome

  • De Toni-Caffey Disease

  • Hyperostosis Cortical Infantile

  • Hyperostosis, Cortical, Congenital
Brittle Bone Disorder

  • Osteogenesis Imperfecta

  • Brittle Bone Disease

  • Fragilitas Ossium

  • Osteopsathyrosis

  • Lobstein Disease

  • Oi

  • Vrolik Disease

  • Lobstein'S Disease

  • Lobstein'S Syndrome

  • Vrolik'S Disease

  • Porak And Durante Disease

  • Glass Bone Disease

  • Osteogenesis Imperfecta, Dominant Perinatal Lethal

  • Osteogenesis Imperfecta, Recessive Perinatal Lethal

  • Brittle Bone Syndrome

  • Oi - [Osteogenesis Imperfecta]

  • Ossium Fragility

  • Osteitis Fragilitans

  • Bony Fragility

  • Blue Sclera With Fragility Of Bone And Deafness

  • White Blue Sclera - Fragility Of Bone - Deafness
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04957 FKBP11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18423 Fkbp11 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24904 Fkbp11 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus FKBP11 RGD RGD:1306161
Canis familiaris FKBP11 VGNC VGNC:40887
Felis catus FKBP11 VGNC VGNC:84020
Bos taurus FKBP11 VGNC VGNC:29018
Mus musculus FKBP11 MGD MGI:1913370
Others FKBP11 NCBI