IWS1 - interacts with SUPT6H, CTD assembly factor 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55677

About IWS1

This gene has 12 transcripts (splice variants), 197 orthologues and 3 paralogues. Ubiquitous expression in testis (RPKM 10.7), lymph node (RPKM 10.6) and 25 other tissues.

Summary

Involved in regulation of histone modification; regulation of mRNA export from nucleus; and regulation of mRNA processing. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

IWS1 Products (2)

mRNA Protein Name
NM_001410923.1 NP_001397852.1 protein IWS1 homolog isoform 2
NM_017969.3 NP_060439.2 protein IWS1 homolog isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17234882 GOA
Biological Process GO Annotation Evidence References Source
involved in chromatin remodeling IMP
IMP: Inferred from mutant phenotype
19141475 GOA
involved in regulation of mRNA export from nucleus IMP
IMP: Inferred from mutant phenotype
17234882 GOA
involved in regulation of mRNA processing IMP
IMP: Inferred from mutant phenotype
17234882 GOA
involved in transcription elongation-coupled chromatin remodeling IMP
IMP: Inferred from mutant phenotype
19141475 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
17234882 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IWS1 Protein Structure

Med26

Med26: TFIIS helical bundle-like domain (636 - 690)

  • 0
  • 200
  • 400
  • 600
  • 819 a.a.
Protein Preferred Names Protein Names

protein IWS1 homolog

  • IWS1 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07002 IWS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22212 Iws1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28734 Iws1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus IWS1 VGNC VGNC:30354
Canis familiaris IWS1 VGNC VGNC:42163
Felis catus IWS1 VGNC VGNC:62990
Mus musculus IWS1 MGD MGI:1920723
Rattus norvegicus IWS1 RGD RGD:1304762
Macaca mulatta IWS1 VGNC VGNC:73651
Others IWS1 NCBI