TTC17 - tetratricopeptide repeat domain 17 Gene

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 55761

About TTC17

Cytogenetic location: 11p12-p11.2 Genomic coordinates (GRCh38): 11:43,358,920-43,494,931 (from NCBI)

This gene has 16 transcripts (splice variants) and 209 orthologues. Ubiquitous expression in thyroid (RPKM 14.5), ovary (RPKM 10.5) and 25 other tissues.

Summary

Involved in Actin filament polymerization and cilium organization. Located in Actin cytoskeleton; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TTC17 Products (6)

mRNA Protein Name
NM_001307943.2 NP_001294872.1 tetratricopeptide repeat protein 17 isoform 2
NM_001376525.1 NP_001363454.1 tetratricopeptide repeat protein 17 isoform 3
NM_001376526.1 NP_001363455.1 tetratricopeptide repeat protein 17 isoform 4
NM_001376527.1 NP_001363456.1 tetratricopeptide repeat protein 17 isoform 5
NM_001376528.1 NP_001363457.1 tetratricopeptide repeat protein 17 isoform 6
NM_018259.6 NP_060729.2 tetratricopeptide repeat protein 17 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
24475127 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in actin filament polymerization IMP
IMP: Inferred from mutant phenotype
24475127 GOA
involved in cilium organization IMP
IMP: Inferred from mutant phenotype
24475127 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
24475127 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
24475127 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
24475127 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TTC17 Protein Structure

TPR_1

TPR_1: Tetratricopeptide repeat (297 - 327)

TPR_11

TPR_11: TPR repeat (659 - 718)

TPR_1

TPR_1: Tetratricopeptide repeat (1088 - 1118)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1141 a.a.
Protein Preferred Names Protein Names

tetratricopeptide repeat protein 17

  • TPR repeat protein 17

関連疾患

Diseases Alias
Pancreatic Squamous Cell Carcinoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS15200 TTC17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Rattus norvegicus TTC17 RGD RGD:1305410
Bos taurus TTC17 VGNC VGNC:36457
Mus musculus TTC17 MGD MGI:1921819
Felis catus TTC17 VGNC VGNC:66654
Canis familiaris TTC17 VGNC VGNC:47940
Macaca mulatta TTC17 VGNC VGNC:79516
Others TTC17 NCBI