MUC13 - mucin 13, cell surface associated Gene

Also Known as DRCC1; MUC-13

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56667

About MUC13

Cytogenetic location: 3q21.2 Genomic coordinates (GRCh38): 3:124,905,442-124,934,751 (from NCBI)

This gene has 5 transcripts (splice variants), 82 orthologues and 2 paralogues. Biased expression in duodenum (RPKM 317.3), small intestine (RPKM 271.9) and 4 other tissues.

Summary

Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008]

MUC13 Products (1)

mRNA Protein Name
NM_033049.4 NP_149038.3 mucin-13 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
11278439 GOA
Biological Process GO Annotation Evidence References Source
involved in maintenance of gastrointestinal epithelium IMP
IMP: Inferred from mutant phenotype
17058067 GOA
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
11278439 GOA
located in cytosol IMP
IMP: Inferred from mutant phenotype
11278439 GOA
located in extracellular space IDA
IDA: Inferred from direct assay
11278439 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MUC13 Protein Structure

SEA

SEA: SEA domain (211 - 321)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 511 a.a.
Protein Preferred Names Protein Names

mucin-13

  • down-regulated in colon cancer 1

MUC13 Antibodies

Cat. No. Product Name Application Reactivity
HY-P82993 MUC13 Antibody (YA2738) IHC-P Human
HY-P82993A MUC13 Antibody (YA2738)(PBS only) IHC-P Human
HY-P84798 MUC13 Antibody (YA4495) WB, IHC-P, FC, ELISA Human, Mouse, Rat
HY-P84798A MUC13 Antibody (YA4495)(PBS only) WB, IHC-P, FC, ELISA Human, Mouse, Rat

Related Diseases

Diseases Alias
Holoprosencephaly 2

  • HPE2

  • Holoprosencephaly-2

  • Holoprosencephaly, Type 2
Bile Duct Cystadenocarcinoma

  • Biliary Cystadenocarcinoma

  • Intrahepatic Bile Duct Cystadenocarcinoma

  • Intrahepatic Bile Duct Mucinous Cystic Neoplasm With An Associated Invasive Carcinoma
Lymphohistiocytoid Mesothelioma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08833 MUC13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-E70295 N-Acetylgalactosaminyltransferase 14 / Unkown
HY-RS22656 Muc13 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29170 Muc13 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus MUC13 VGNC VGNC:68358
Mus musculus MUC13 MGD MGI:103190
Rattus norvegicus MUC13 RGD RGD:708547
Macaca mulatta MUC13 VGNC VGNC:84151
Canis familiaris MUC13 VGNC VGNC:43498
Bos taurus MUC13 VGNC VGNC:31758
Others MUC13 NCBI