2. Gene
  3. LRTM1 - leucine rich repeats and transmembrane domains 1 Gene

LRTM1 - leucine rich repeats and transmembrane domains 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HT017

Gene ID: 57408 | Gene type: protein coding

About LRTM1

This gene has 2 transcripts (splice variants), 193 orthologues and 22 paralogues. Biased expression in spleen (RPKM 2.9), esophagus (RPKM 1.8) and 1 other tissue.

Summary

Predicted to enable Roundabout binding activity and heparin binding activity. Predicted to be involved in axon guidance and negative chemotaxis. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

LRTM1 Products(2)

mRNA Protein Name
NM_001304389.2 NP_001291318.1 leucine-rich repeat and transmembrane domain-containing protein 1 isoform 2
NM_020678.4 NP_065729.1 leucine-rich repeat and transmembrane domain-containing protein 1 isoform 1 precursor

LRTM1 Protein Structure

LRR_8

LRR_8: Leucine rich repeat (76 - 134)

  • 0
  • 100
  • 200
  • 300
  • 345 a.a.
Protein Preferred Names Protein Names

leucine-rich repeat and transmembrane domain-containing protein 1

Related Diseases

Diseases Alias
Congenital Fiber-Type Disproportion

Congenital Fiber Type Disproportion

Cftdm

Congenital Myopathy With Fiber Type Disproportion

Cftd

Congenital Fiber-Type Disproportion Myopathy

Fiber-Type Disproportion Myopathy, Congenital

Myopathy, Congenital With Fiber-Type Disproportion
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07846 LRTM1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris LRTM1 VGNC VGNC:49805
Rattus norvegicus LRTM1 RGD RGD:2321691
Mus musculus LRTM1 MGD MGI:2442106
Macaca mulatta LRTM1 VGNC VGNC:82179
Felis catus LRTM1 VGNC VGNC:80616
Bos taurus LRTM1 VGNC VGNC:31046