CPNE5 - copine 5 Gene

Also Known as CPN5; COPN5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57699

About CPNE5

Cytogenetic location: 6p21.2 Genomic coordinates (GRCh38): 6:36,740,775-36,839,998 (from NCBI)

This gene has 8 transcripts (splice variants), 278 orthologues and 8 paralogues. Biased expression in brain (RPKM 15.7), lymph node (RPKM 8.6) and 9 other tissues.

Summary

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an Integrin A domain-like sequence in the C-terminus. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. More variants may exist, but their full-length natures could not be determined. [provided by RefSeq, Sep 2015]

CPNE5 Products (14)

mRNA Protein Name
NM_001314017.1 NP_001300946.1 copine-5 isoform b
NM_001314018.2 NP_001300947.1 copine-5 isoform c
NM_001314019.2 NP_001300948.1 copine-5 isoform d
NM_001314020.2 NP_001300949.1 copine-5 isoform d
NM_001376888.1 NP_001363817.1 copine-5 isoform d
NM_001376889.1 NP_001363818.1 copine-5 isoform e
NM_001376890.1 NP_001363819.1 copine-5 isoform c
NM_001376891.1 NP_001363820.1 copine-5 isoform f
NM_001376892.1 NP_001363821.1 copine-5 isoform g
NM_001376893.1 NP_001363822.1 copine-5 isoform g
NM_001376894.1 NP_001363823.1 copine-5 isoform i
NM_001376895.1 NP_001363824.1 copine-5 isoform h
NM_001410887.1 NP_001397816.1 copine-5 isoform j
NM_020939.2 NP_065990.1 copine-5 isoform a

CPNE5 Protein Structure

C2

C2: C2 domain (29 - 115)

C2

C2: C2 domain (183 - 267)

Copine

Copine: Copine (347 - 491)

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  • 593 a.a.
Protein Preferred Names Protein Names

copine-5

  • copine V

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03107 CPNE5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21538 Cpne5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28056 Cpne5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CPNE5 VGNC VGNC:27661
Felis catus CPNE5 VGNC VGNC:61132
Mus musculus CPNE5 MGD MGI:2385908
Macaca mulatta CPNE5 VGNC VGNC:71467
Canis familiaris CPNE5 VGNC VGNC:39564
Rattus norvegicus CPNE5 RGD RGD:1308021
Others CPNE5 NCBI