PDE2A - phosphodiesterase 2A Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 609574

About PDE2A

Primary_assembly 21: 25,751,765-25,844,666 forward strand.ROS_Cfam_1.0:CM025120.1

This gene has 3 transcripts (splice variants), 215 orthologues and 22 paralogues.

PDE2A Products (14)

mRNA Protein Name
XM_038430216.1 XP_038286144.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X4
XM_038430220.1 XP_038286148.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X6
XM_038430214.1 XP_038286142.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X3
XM_038430217.1 XP_038286145.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1
XM_038430218.1 XP_038286146.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X5
XM_038430219.1 XP_038286147.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X5
XM_038430221.1 XP_038286149.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X2
XM_038430214.1 XP_038286142.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X3
XM_038430216.1 XP_038286144.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X4
XM_038430219.1 XP_038286147.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X5
XM_038430221.1 XP_038286149.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X2
XM_038430217.1 XP_038286145.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1
XM_038430218.1 XP_038286146.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X5
XM_038430220.1 XP_038286148.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X6

PDE2A Protein Structure

GAF

GAF: smart00065 (342 - 489)

GAF

GAF: smart00065 (511 - 660)

PDEase_I

PDEase_I: pfam00233 (757 - 990)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1044 a.a.
Protein Preferred Names Protein Names

cGMP-dependent 3',5'-cyclic phosphodiesterase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-112831 Osoresnontrine Inhibitor 99.94% Phase 2
HY-111167 AN-2898 Inhibitor / Phase 2
HY-111371 PF-05180999 Inhibitor 99.96% Phase 1
HY-103493 TAK-915 Inhibitor 99.57% Phase 1

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-102050 PF-05085727 Inhibitor 99.53% Unkown
HY-132993 Hcyb1 Inhibitor 98.20% Unkown
HY-U00427 PDE2A-IN-3 Inhibitor 99.88% Unkown
HY-102043 PDM-631 Inhibitor / Unkown
HY-112704 PDE5-IN-2 Inhibitor / Unkown
HY-120710 DNS-8254 Inhibitor / Unkown
HY-142660 PDE2A-IN-1 Inhibitor / Unkown
HY-168966 JNJ-54082730 / Unkown
HY-180526 PDE2A-IN-2 Inhibitor / Unkown
HY-RS10213 PDE2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10214 Pde2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10215 Pde2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-124173 PF-06815189 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PDE2A NCBI NCBI:5138