S1PR5 - sphingosine-1-phosphate receptor 5 Gene

Canis lupus familiaris (sub-species: familiaris)

Also known as EDG8

Gene ID: 610828 | Gene type: protein coding

About S1PR5

Primary_assembly 20: 51,165,296-51,168,809 forward strand.ROS_Cfam_1.0:CM025119.1

This gene has 1 transcript (splice variant), 236 orthologues and 16 paralogues.

mRNA	Protein	Name
XM_038428646.1	XP_038284574.1	sphingosine 1-phosphate receptor 5
XM_038428644.1	XP_038284572.1	sphingosine 1-phosphate receptor 5
XM_038428645.1	XP_038284573.1	sphingosine 1-phosphate receptor 5

7tm_GPCRs

Protein Preferred Names

Protein Names

sphingosine 1-phosphate receptor 5

endothelial differentiation, sphingolipid G-protein-coupled receptor, 8

Approval

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-12355	Siponimod	Agonist	99.95%	Yes
HY-12288	Ozanimod	Agonist	99.98%	Yes
HY-10569	Ponesimod	Agonist	99.78%	Yes
HY-12288A	Ozanimod hydrochloride	Modulator	98.10%	Yes
HY-12355A	Siponimod hemifumarate	Agonist	99.64%	Yes

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-17606	Cenerimod	Agonist	99.43%	Phase 3

Pre-clinical Phase

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-111253	CYM-5478	Agonist	99.90%	Unkown
HY-136578	RP101988	Agonist	98.80%	Unkown
HY-176533	S1PR5-IN-1	Inhibitor	99.58%	Unkown
HY-136576	RP101075	Agonist	99.19%	Unkown
HY-148115	S1p receptor agonist 2	Agonist	/	Unkown
HY-148198	S1P5 receptor agonist-1	Agonist	/	Unkown
HY-136577	RP101442	Agonist	/	Unkown
HY-14402	AMG 369	Agonist	/	Unkown
HY-181875	S1PR1/S1PR5 agonist-1	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	S1PR5	NCBI	NCBI:53637

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