Ube2w - ubiquitin-conjugating enzyme E2W (putative) Gene

Also Known as 6130401J04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66799

Summary

Enables ubiquitin conjugating enzyme activity and ubiquitin protein Ligase binding activity. Involved in cellular response to misfolded protein; protein monoubiquitination; and proteolysis involved in cellular protein catabolic process. Located in nucleus. Orthologous to human UBE2W (ubiquitin conjugating enzyme E2 W). [provided by Alliance of Genome Resources, Apr 2022]

Ube2w Products (3)

mRNA Protein Name
NM_001271016.2 NP_001257945.2 ubiquitin-conjugating enzyme E2 W isoform 2
NM_001271017.2 NP_001257946.2 ubiquitin-conjugating enzyme E2 W isoform 3
NM_025773.4 NP_080049.3 ubiquitin-conjugating enzyme E2 W isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21229326 MGI
enables ubiquitin conjugating enzyme activity IDA
IDA: Inferred from direct assay
21229326 MGI
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
21855799 MGI
enables ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
21229326 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to misfolded protein IMP
IMP: Inferred from mutant phenotype
21855799 MGI
involved in proteasome-mediated ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
21855799 MGI
involved in protein monoubiquitination IDA
IDA: Inferred from direct assay
21855799 MGI
involved in protein monoubiquitination IMP
IMP: Inferred from mutant phenotype
21229326 MGI
involved in protein quality control for misfolded or incompletely synthesized proteins IMP
IMP: Inferred from mutant phenotype
21855799 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
21229326 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin-conjugating enzyme E2 W

  • E2 ubiquitin-conjugating enzyme W

  • N-terminal E2 ubiquitin-conjugating enzyme

  • N-terminus-conjugating E2

  • probable ubiquitin-conjugating enzyme E2 W

  • ubiquitin carrier protein W

  • ubiquitin-protein ligase W

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15366 UBE2W Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20124 Ube2w Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26628 Ube2w Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ube2w NCBI NCBI:55284