Dgki - diacylglycerol kinase, iota Gene

Also Known as rDGKi-3

Species: Rattus norvegicus

Gene Type: protein coding

Gene ID: 688705

Summary

Enables diacylglycerol kinase activity. Involved in diacylglycerol metabolic process; lipid phosphorylation; and phosphatidic acid biosynthetic process. Located in several cellular components, including excitatory synapse; neuronal cell body; and postsynaptic density. Is active in glutamatergic synapse and synaptic vesicle. Is extrinsic component of postsynaptic density membrane and extrinsic component of presynaptic active zone membrane. Orthologous to human DGKI (diacylglycerol kinase iota). [provided by Alliance of Genome Resources, Apr 2022]

Dgki Products (1)

mRNA	Protein	Name
NM_198782.2	NP_942077.2	diacylglycerol kinase iota

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables ATP-dependent diacylglycerol kinase activity	IDA IDA: Inferred from direct assay	15024004	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	21119615	RGD

Biological Process GO Annotation	Evidence	References	Source
involved in diacylglycerol metabolic process	IDA IDA: Inferred from direct assay	15024004	RGD
involved in lipid phosphorylation	IDA IDA: Inferred from direct assay	15024004	RGD
involved in phosphatidic acid biosynthetic process	IDA IDA: Inferred from direct assay	15024004	RGD

Cellular Component GO Annotation	Evidence	References	Source
located in axon terminus	IDA IDA: Inferred from direct assay	21119615	RGD
located in cytosol	IDA IDA: Inferred from direct assay	21119615	RGD
located in excitatory synapse	IDA IDA: Inferred from direct assay	21119615	RGD
is active in extrinsic component of postsynaptic density membrane	IDA IDA: Inferred from direct assay	21119615	RGD
is active in extrinsic component of presynaptic active zone membrane	IDA IDA: Inferred from direct assay	21119615	RGD
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	21119615	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	21119615	RGD
located in postsynaptic density	IDA IDA: Inferred from direct assay	21119615	RGD
located in presynaptic active zone	IDA IDA: Inferred from direct assay	21119615	RGD
located in synaptic membrane	IDA IDA: Inferred from direct assay	21119615	RGD
is active in synaptic vesicle	IDA IDA: Inferred from direct assay	21119615	RGD
located in synaptic vesicle	IDA IDA: Inferred from direct assay	21119615	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
diacylglycerol kinase iota	DAG kinase iota DGK-iota diacylglycerol kinase iota-3 diglyceride kinase iota

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03721	DGKI Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22136	Dgki Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS28657	Dgki Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dgki	NCBI	NCBI:9162