Antxr1 - anthrax toxin receptor 1 Gene

Also Known as Tem8; Antrx1; 2310008J16Rik; 2810405N18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69538

Summary

Predicted to enable actin filament binding activity; Collagen binding activity; and transmembrane signaling receptor activity. Acts upstream of or within several processes, including blood vessel development; negative regulation of extracellular matrix assembly; and positive regulation of metallopeptidase activity. Predicted to be located in external side of plasma membrane; filopodium membrane; and lamellipodium membrane. Predicted to be active in cell surface and plasma membrane. Is expressed in choroid plexus and lung. Human ortholog(s) of this gene implicated in GAPO syndrome and colorectal carcinoma. Orthologous to human ANTXR1 (ANTXR cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Antxr1 Products (1)

mRNA Protein Name
NM_054041.2 NP_473382.1 anthrax toxin receptor 1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within blood vessel development IMP
IMP: Inferred from mutant phenotype
25572963 MGI
acts upstream of or within negative regulation of extracellular matrix assembly IMP
IMP: Inferred from mutant phenotype
25572963 MGI
acts upstream of or within positive regulation of metallopeptidase activity IMP
IMP: Inferred from mutant phenotype
25572963 MGI
acts upstream of or within reproductive process IMP
IMP: Inferred from mutant phenotype
19617532 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

anthrax toxin receptor 1

  • tumor endothelial marker 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-183806 ANTXR1-IN-1 Inducer / Unkown
HY-RS00755 ANTXR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18085 Antxr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24559 Antxr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992306 Anti-TEM8 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Antxr1 NCBI NCBI:84168