DOT1L - DOT1 like histone lysine methyltransferase Gene

Macaca mulatta

Gene ID: 710033 | Gene type: protein coding

About DOT1L

Primary_assembly 19: 2,006,282-2,075,544 forward strand.Mmul_10:CM014354.1

This gene has 4 transcripts (splice variants) and 205 orthologues.

mRNA	Protein	Name
XM_015122411.2	XP_014977897.1	histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X5
XM_015122409.2	XP_014977895.1	histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X2
XM_028838672.1	XP_028694505.1	histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
XM_028838675.1	XP_028694508.1	histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X4
XM_028838674.1	XP_028694507.1	histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X3

Protein Preferred Names

Protein Names

histone-lysine N-methyltransferase, H3 lysine-79 specific

DOT1-like, histone H3 methyltransferase

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-15593	Pinometostat	Inhibitor	99.99%	Phase 2

Pre-clinical Phase

Bioactive Molecules (17)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15227	EPZ004777	Inhibitor	99.74%	Unkown
HY-15650	SGC0946	Inhibitor	99.68%	Unkown
HY-135127	Dot1L-IN-4	Inhibitor	99.67%	Unkown
HY-141877	MS4322	Degrader	99.14%	Unkown
HY-15227A	EPZ004777 hydrochloride	Inhibitor	98.92%	Unkown
HY-135128	Dot1L-IN-5	Inhibitor	99.82%	Unkown
HY-121093	DC-S239	Inhibitor	99.73%	Unkown
HY-101520A	Dot1L-IN-1 TFA	Inhibitor	99.59%	Unkown
HY-141877B	MS4322 (isomer)		99.87%	Unkown
HY-181789	DOT1L808	Degrader	/	Unkown
HY-101520	Dot1L-IN-1	Inhibitor	/	Unkown
HY-168083	Dot1L-IN-9	Inhibitor	/	Unkown
HY-145813	MU1656	Inhibitor	/	Unkown
HY-146724	Dot1L-IN-7	Inhibitor	/	Unkown
HY-181790	DOT1L ligand-2	Ligand	/	Unkown
HY-115619	EPZ004777 formate	Inhibitor	/	Unkown
HY-15650A	SGC0946 TFA	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	DOT1L	NCBI	NCBI:84444

Name
Email *

	Sorry, but the email address you supplied was invalid.