Dot1L-IN-9
Dot1L-IN-9 (Compound 12) is a DOT1L inhibitor (IC50: 125 nM). Dot1L-IN-9 reduces H3K79 dimethylation. Dot1L-IN-9 can be used for anti-leukemia research.
For research use only. We do not sell to patients.
- Formula: C28H38N8O3
- Molecular Weight:534.65
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Histone Methyltransferase Isoforms
More
Biological Activity
|
DOT1L 125 nM (IC50) |
Chemical Information
-
Molecular Weight 534.65
-
Formula C28H38N8O3
-
SMILES
NC1=C2N=CN(C2=NC=N1)[C@@H]3O[C@H](CN4CCC(CCC5=NC6=CC(C(C)(C)C)=CC=C6N5)CC4)[C@@H](O)[C@H]3O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)