Arhgap42 - Rho GTPase activating protein 42 Gene

Also Known as 9030420J04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71544

Summary

Enables GTPase activator activity. Acts upstream of or within negative regulation of Rho protein signal transduction; negative regulation of systemic arterial blood pressure; and negative regulation of vascular associated smooth muscle contraction. Orthologous to human ARHGAP42 (Rho GTPase activating protein 42). [provided by Alliance of Genome Resources, Apr 2022]

Arhgap42 Products (9)

mRNA Protein Name
NM_001372563.1 NP_001359492.1 rho GTPase-activating protein 42 isoform 1
NM_001372564.1 NP_001359493.1 rho GTPase-activating protein 42 isoform 2
NM_001372565.1 NP_001359494.1 rho GTPase-activating protein 42 isoform 4
NM_001372566.1 NP_001359495.1 rho GTPase-activating protein 42 isoform 5
NM_001372567.1 NP_001359496.1 rho GTPase-activating protein 42 isoform 6
NM_001372568.1 NP_001359497.1 rho GTPase-activating protein 42 isoform 7
NM_001372569.1 NP_001359498.1 rho GTPase-activating protein 42 isoform 8
NM_001372570.1 NP_001359499.1 rho GTPase-activating protein 42 isoform 9
NM_027823.2 NP_082099.1 rho GTPase-activating protein 42 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
24335996 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of Rho protein signal transduction IMP
IMP: Inferred from mutant phenotype
24335996 MGI
acts upstream of or within negative regulation of systemic arterial blood pressure IGI
IGI: Inferred from genetic interaction
24335996 MGI
acts upstream of or within negative regulation of vascular associated smooth muscle contraction IMP
IMP: Inferred from mutant phenotype
24335996 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho GTPase-activating protein 42

  • VRho GTPase activating protein 42

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00936 ARHGAP42 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22058 Arhgap42 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28576 Arhgap42 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgap42 NCBI NCBI:143872