Nsun4 - NOL1/NOP2/Sun domain family, member 4 Gene

Also Known as Shtap; 2310010O12Rik; 2810405F18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72181

Summary

Enables small ribosomal subunit rRNA binding activity. Involved in mature ribosome assembly; positive regulation of mitochondrial translation; and rRNA methylation. Located in mitochondrion. Is expressed in several structures, including branchial arch; central nervous system; limb bud; neural ectoderm; and sensory organ. Orthologous to human NSUN4 (NOP2/Sun RNA methyltransferase 4). [provided by Alliance of Genome Resources, Apr 2022]

Nsun4 Products (3)

mRNA Protein Name
NM_001369075.1 NP_001356004.1 putative methyltransferase NSUN4 isoform b
NM_001369076.1 NP_001356005.1 putative methyltransferase NSUN4 isoform b
NM_028142.5 NP_082418.1 putative methyltransferase NSUN4 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables small ribosomal subunit rRNA binding IDA
IDA: Inferred from direct assay
24516400 MGI
Biological Process GO Annotation Evidence References Source
involved in cytosolic ribosome assembly IMP
IMP: Inferred from mutant phenotype
24516400 MGI
involved in positive regulation of mitochondrial translation IMP
IMP: Inferred from mutant phenotype
24516400 MGI
involved in rRNA methylation IMP
IMP: Inferred from mutant phenotype
24516400 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
21531335 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

putative methyltransferase NSUN4

  • 5-methylcytosine tRNA methyltransferase NSUN4

  • sperm head and tail associated protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09603 NSUN4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22692 Nsun4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29206 Nsun4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nsun4 NCBI NCBI:387338