NOTCH1 - notch receptor 1 Gene
Species: Bos taurus
About NOTCH1
This gene has 2 transcripts (splice variants), 273 orthologues and 3 paralogues.
NOTCH1 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| XM_024999642.1 | XP_024855410.1 | neurogenic locus notch homolog protein 1 isoform X1 |
| XM_024999644.1 | XP_024855412.1 | neurogenic locus notch homolog protein 1 isoform X3 |
| XM_024999643.1 | XP_024855411.1 | neurogenic locus notch homolog protein 1 isoform X2 |
NOTCH1 Protein Structure
EGF_CA: cd00054 (179 - 212)
EGF_CA: cd00054 (215 - 253)
EGF_CA: cd00054 (260 - 292)
EGF_CA: cd00054 (294 - 330)
EGF_CA: cd00054 (332 - 369)
EGF_CA: cd00054 (372 - 407)
EGF_CA: cd00054 (449 - 487)
EGF_CA: cd00054 (489 - 525)
EGF_CA: cd00054 (527 - 563)
EGF_CA: cd00054 (565 - 601)
EGF_CA: cd00054 (603 - 638)
EGF_CA: cd00054 (640 - 676)
EGF_CA: cd00054 (678 - 712)
EGF_CA: cd00054 (715 - 750)
EGF_CA: cd00054 (754 - 787)
EGF_CA: cd00054 (792 - 826)
EGF_CA: cd00054 (828 - 864)
EGF_CA: cd00054 (906 - 942)
EGF_CA: cd00054 (944 - 980)
EGF_CA: cd00054 (982 - 1018)
EGF_CA: cd00054 (1025 - 1056)
EGF_CA: cd00054 (1058 - 1094)
EGF_CA: cd00054 (1151 - 1180)
EGF_CA: cd00054 (1183 - 1217)
EGF_CA: cd00054 (1221 - 1256)
EGF_CA: cd00054 (1266 - 1302)
EGF_CA: cd00054 (1304 - 1342)
NL: smart00004 (1479 - 1516)
Notch: pfam00066 (1524 - 1559)
NL: smart00004 (1558 - 1598)
NOD: pfam06816 (1603 - 1658)
NODP: pfam07684 (1696 - 1752)
JMTM_Notch1: cd21702 (1745 - 1824)
ANKYR: COG0666 (1898 - 2007)
ANK: sd00045 (1905 - 1950)
ANK: sd00045 (1952 - 1983)
ANKYR: COG0666 (1956 - 2146)
Ank_2: pfam12796 (1957 - 2050)
ANK: sd00045 (1985 - 2016)
ANK: sd00045 (2019 - 2050)
ANK: sd00045 (2052 - 2083)
ANK: sd00045 (2085 - 2116)
PHA03247: cl33720 (2146 - 2505)
- 0
- 400
- 800
- 1200
- 1600
- 2000
- 2400
- 2570 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
neurogenic locus notch homolog protein 1 |
|
|
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-10585 | Valproic acid | 99.90% | Unkown | |
| HY-10585A | Valproic acid sodium | 99.65% | Unkown | |
| HY-10585AR | Valproic acid sodium (Standard) | 98.92% | Unkown | |
| HY-10585B | Valproic acid sodium (2:1) | / | Unkown |
Clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-N0711 | Carvacrol | 99.98% | Phase 3 | |
| HY-15670 | BMS-906024 | Inhibitor | 99.91% | Phase 1 |
| HY-12860 | BMS-986115 | Inhibitor | 99.90% | Phase 1 |
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-P99258 | Brontictuzumab | Inhibitor | 95.00% | Phase 1 |
| HY-P991423 | MEDI0639 | Inhibitor | 98.78% | Phase 1 |
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-13027 | DAPT | 99.97% | Unkown | |
| HY-N0133 | Tangeretin | 99.36% | Unkown | |
| HY-134978A | (+)SHIN2 | Inhibitor | 99.30% | Unkown |
| HY-N0232 | Psoralidin | 99.90% | Unkown | |
| HY-124284 | Hexamethylene bisacetamide | 99.56% | Unkown | |
| HY-N5112B | β,β-Dimethylacrylshikonin | 99.30% | Unkown | |
| HY-14174 | MRK-560 | Inhibitor | 99.92% | Unkown |
| HY-10585R | Valproic acid (Standard) | 99.97% | Unkown | |
| HY-164404 | NADI-351 | Inhibitor | 99.83% | Unkown |
| HY-10585S2 | Valproic acid-d15 | 99.80% | Unkown | |
| HY-N1510 | Kaempferol 3-O-gentiobioside | Inhibitor | 99.88% | Unkown |
| HY-10585S1 | Valproic acid-d6 | 99.83% | Unkown | |
| HY-144899 | ASR-490 | Inhibitor | 99.20% | Unkown |
| HY-10585S | Valproic acid-d4 | 98.0% | Unkown | |
| HY-12465 | Z-Ile-Leu-aldehyde | 97.0% | Unkown | |
| HY-N11709 | Theasaponin E1 | 98.68% | Unkown | |
| HY-N2896 | Arjunolic acid | 98.83% | Unkown | |
| HY-10585S4 | Valproic acid-d4-1 | 99.5% | Unkown | |
| HY-P1985 | Notch 1 | 95.39% | Unkown | |
| HY-10585AS1 | Valproic acid-d14 sodium | 96.73% | Unkown | |
| HY-164466 | CAD204520 | Inhibitor | 99.22% | Unkown |
| HY-164466A | CAD204520 dihydrochloride | Inhibitor | 99.26% | Unkown |
| HY-P1985A | Notch 1 TFA | / | Unkown | |
| HY-RS09445 | NOTCH1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-141876 | PRT543 | / | Unkown | |
| HY-183626 | PAI-1-IN-1 | 99.45% | Unkown | |
| HY-10585AS | Valproic acid-d7 sodium | / | Unkown | |
| HY-103539 | 3,5-Bis(4-nitrophenoxy)benzoic acid | Inhibitor | 98.50% | Unkown |
| HY-10585AG | Valproic acid sodium (GMP) | / | Unkown | |
| HY-10585S3 | Valproic acid-d4 sodium | / | Unkown | |
| HY-118900 | CP-654577 | / | Unkown | |
| HY-120372 | BMS-871 | Inhibitor | / | Unkown |
| HY-181975 | ATOX1-IN-1 | Inhibitor | / | Unkown |
| HY-E70178 | Protein O-Glucosyltransferase 1 | / | Unkown | |
| HY-N9790 | Procyanidin B2 3,3'-di-O-gallate | Inhibitor | / | Unkown |
| HY-RS09446 | Notch1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS09447 | Notch1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-W794759 | Valproic acid magnesium | / | Unkown | |
| HY-N12768 | Rhodojaponin VI | Inhibitor | / | Unkown |
| HY-W714200 | Neburon | / | Unkown |
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P991328 | MAb604.107 | Inhibitor | / | Unkown |
| HY-P992275 | Anti-Nicastrin Antibody (A5226A) | Inhibitor | / | Unkown |
| HY-P990476 | Anti-NOTCH1 Antibody | Inhibitor | / | Unkown |
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