Asic1 - acid sensing ion channel subunit 1 Gene

Also Known as Accn2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 79123

Summary

Enables inorganic cation transmembrane transporter activity and ion channel activity. Involved in ion transmembrane transport. Acts upstream of or within inorganic cation transmembrane transport. Located in cell surface. Is integral component of membrane. Orthologous to human ASIC1 (acid sensing ion channel subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Asic1 Products (1)

mRNA Protein Name
NM_024154.2 NP_077068.1 acid-sensing ion channel 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables inorganic cation transmembrane transporter activity IDA
IDA: Inferred from direct assay
11448963 RGD
enables monoatomic ion channel activity IDA
IDA: Inferred from direct assay
9707631 RGD
enables pH-gated monoatomic ion channel activity IDA
IDA: Inferred from direct assay
11448963 RGD
Biological Process GO Annotation Evidence References Source
acts upstream of or within inorganic cation transmembrane transport IDA
IDA: Inferred from direct assay
11448963 RGD
involved in monoatomic ion transmembrane transport IMP
IMP: Inferred from mutant phenotype
19074149 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
19074149 RGD
located in membrane IDA
IDA: Inferred from direct assay
11448963 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acid-sensing ion channel 1

  • BNaC2

  • acid-sensing (proton-gated) ion channel 1

  • amiloride-sensitive cation channel 2, neuronal

  • brain sodium channel 2

  • proton gated cation channel ASIC1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (17)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1411 Psalmotoxin 1 99.20% Unkown
HY-131879 NS383 99.83% Unkown
HY-164284 LK-2 Antagonist 98.83% Unkown
HY-P5174 MitTx Activator 98.0% Unkown
HY-176550 ASIC1a antagonist-1 Antagonist 98.00% Unkown
HY-P1411A Psalmotoxin 1 TFA 99.37% Unkown
HY-P1441A Mambalgin 1 TFA Inhibitor 95.72% Unkown
HY-131261 Ibuprofen alcohol / Unkown
HY-155017 6-Iodoamiloride Inhibitor / Unkown
HY-P10977 Tat-ASIC1a (1-20) (mouse, rat) Inhibitor / Unkown
HY-P5172 MitTx-alpha Agonist / Unkown
HY-P5780 π-TRTX-Hm3a Inhibitor / Unkown
HY-P5899 Mambalgin-3 Inhibitor / Unkown
HY-RS01089 ASIC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W703632 2-(4-Isobutylphenyl)propan-3,3,3-d3-1-ol / Unkown
HY-RS17600 Asic1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24060 Asic1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Asic1 NCBI NCBI:41