Chrna1 - cholinergic receptor nicotinic alpha 1 subunit Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 79557

Summary

Enables acetylcholine-gated cation-selective channel activity. Involved in cation transport and skeletal muscle contraction. Part of acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 1A and congenital myasthenic syndrome 1B. Orthologous to human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrna1 Products (1)

mRNA Protein Name
NM_024485.2 NP_077811.1 acetylcholine receptor subunit alpha precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables acetylcholine-gated monoatomic cation-selective channel activity IDA
IDA: Inferred from direct assay
1702709 RGD
Biological Process GO Annotation Evidence References Source
involved in monoatomic cation transport IDA
IDA: Inferred from direct assay
22461452 RGD
involved in skeletal muscle contraction IDA
IDA: Inferred from direct assay
22461452 RGD
Cellular Component GO Annotation Evidence References Source
part of acetylcholine-gated channel complex IDA
IDA: Inferred from direct assay
22461452 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acetylcholine receptor subunit alpha

  • cholinergic receptor nicotinic alpha polypeptide 1

  • cholinergic receptor, nicotinic, alpha 1 (muscle)

  • cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02665 CHRNA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17513 Chrna1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23970 Chrna1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chrna1 NCBI NCBI:1134