Ntng1 - netrin G1 Gene

Also Known as Lmnt1; A930010C08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 80883

Summary

Predicted to enable cell-cell adhesion mediator activity. Involved in several processes, including regulation of cell projection organization; regulation of neuron migration; and synaptic membrane adhesion. Acts upstream of or within axonogenesis. Located in Schaffer collateral - CA1 synapse and plasma membrane. Is anchored component of presynaptic active zone membrane. Is active in glutamatergic synapse. Is expressed in brain and enteric nervous system. Orthologous to human NTNG1 (netrin G1). [provided by Alliance of Genome Resources, Apr 2022]

Ntng1 Products (5)

mRNA Protein Name
NM_001163348.1 NP_001156820.1 netrin-G1 isoform b precursor
NM_001163349.1 NP_001156821.1 netrin-G1 isoform c precursor
NM_001163350.1 NP_001156822.1 netrin-G1 isoform d precursor
NM_030699.2 NP_109624.1 netrin-G1 isoform a precursor
NM_133488.1 NP_597995.1 netrin-G1 isoform e precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16980967 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within axonogenesis IDA
IDA: Inferred from direct assay
11804778 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
25411505 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
25411505 MGI
involved in regulation of neuron migration IMP
IMP: Inferred from mutant phenotype
31692205 MGI
involved in regulation of neuron projection arborization IMP
IMP: Inferred from mutant phenotype
31692205 MGI
involved in regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
31692205 MGI
involved in synaptic membrane adhesion IDA
IDA: Inferred from direct assay
25411505 MGI
involved in synaptic membrane adhesion IEP
IEP: Inferred from expression pattern
25411505 MGI
involved in synaptic membrane adhesion IMP
IMP: Inferred from mutant phenotype
25411505 MGI
Cellular Component GO Annotation Evidence References Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
25411505 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
25411505 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
25411505 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
25411505 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10964959 MGI
is active in presynaptic active zone membrane IDA
IDA: Inferred from direct assay
25411505 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

netrin-G1

  • laminet-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS20458 Ntng1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09625 NTNG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09626 NTNG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26967 Ntng1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ntng1 NCBI NCBI:22854