GPR63 - G protein-coupled receptor 63 Gene

Also Known as PSP24B; PSP24(beta)

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 81491

About GPR63

Cytogenetic location: 6q16.1 Genomic coordinates (GRCh38): 6:96,794,125-96,837,477 (from NCBI)

This gene has 1 transcript (splice variant), 188 orthologues and 3 paralogues. Broad expression in testis (RPKM 1.6), brain (RPKM 1.0) and 21 other tissues.

Summary

This gene encodes a G protein-coupled receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]

GPR63 Products (2)

mRNA Protein Name
NM_001143957.3 NP_001137429.1 probable G-protein coupled receptor 63
NM_030784.4 NP_110411.1 probable G-protein coupled receptor 63

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
part of receptor complex IDA
IDA: Inferred from direct assay
23382219 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPR63 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (98 - 371)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 419 a.a.
Protein Preferred Names Protein Names

probable G-protein coupled receptor 63

  • PSP24-2

Related Diseases

Diseases Alias
Branchiooculofacial Syndrome

  • Branchio-Oculo-Facial Syndrome

  • BOFS

  • Bof Syndrome

  • Hemangiomatous Branchial Clefts-Lip Pseudocleft Syndrome

  • Lip Pseudocleft-Hemangiomatous Branchial Cyst Syndrome

  • Branchial Clefts With Characteristic Facies, Growth Retardation, Imperforate Nasolacrimal Duct, And Premature Aging

  • Branchial Clefts With Characteristic Facies Growth Retardation Imperforate Nasolacrimal Duct And Premature Aging

  • Bofs Syndrome

  • Lip Pseudocleft-Hemagiomatous Branchial Cyst Syndrome
Spina Bifida Occulta
Gilles De La Tourette Syndrome

  • Tourette Syndrome

  • Tourette Disorder

  • GTS

  • Ts

  • Gilles De La Tourette'S Syndrome

  • Motor-Verbal Tic Disorder

  • Guinon'S Disease

  • Psychogenic Tics

  • Tourette'S Syndrome

  • Chronic Motor And Vocal Tic Disorder

  • Td

  • Tourette'S Disease

  • Combined Vocal And Multiple Motor Tic Disorder [De La Tourette]

  • Combined Vocal And Multiple Motor Tic Disorder

  • Tic De La Tourette
Intracranial Berry Aneurysm

  • Familial Aneurysmal Subarachnoid Hemorrhage

  • Familial Berry Aneurysm

  • Familial Intracranial Saccular Aneurysm

  • Saccular Cerebral Aneurysm

  • Aneurysm, Intracranial Berry

  • Aneurysmal Subarachnoid Hemorrhage

  • Aneurysm, Intracranial Berry, 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05729 GPR63 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22537 Gpr63 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29057 Gpr63 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris GPR63 VGNC VGNC:41441
Macaca mulatta GPR63 VGNC VGNC:81074
Rattus norvegicus GPR63 RGD RGD:1306460
Felis catus GPR63 VGNC VGNC:62693
Mus musculus GPR63 MGD MGI:2135884
Bos taurus GPR63 VGNC VGNC:29595
Others GPR63 NCBI