Kremen1 - kringle containing transmembrane protein 1 Gene

Also Known as Krm1; Kremen

Species: Mus musculus

Gene Type: protein coding
Gene ID: 84035

Summary

Involved in several processes, including negative regulation of axon regeneration; negative regulation of canonical Wnt signaling pathway; and negative regulation of ossification. Located in neuronal cell body. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb ectoderm; and sensory organ. Human ortholog(s) of this gene implicated in ectodermal dysplasia 13. Orthologous to human KREMEN1 (kringle containing transmembrane protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Kremen1 Products (1)

mRNA Protein Name
NM_032396.3 NP_115772.2 kremen protein 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
26206087 MGI
involved in limb development IMP
IMP: Inferred from mutant phenotype
18505822 MGI
involved in negative regulation of axon regeneration IMP
IMP: Inferred from mutant phenotype
24167472 MGI
involved in negative regulation of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
26206087 MGI
involved in negative regulation of ossification IMP
IMP: Inferred from mutant phenotype
18505822 MGI
Cellular Component GO Annotation Evidence References Source
located in neuronal cell body IDA
IDA: Inferred from direct assay
24167472 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kremen protein 1

  • dickkopf receptor

  • kringle domain-containing transmembrane protein 1

  • kringle-coding gene marking the eye and the nose

  • kringle-containing protein marking the eye and the nose

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07428 KREMEN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20635 Kremen1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27144 Kremen1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kremen1 NCBI NCBI:83999