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Cat. No.: HY-19268

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GG-818

Name: GG-818
Brand: MedChemExpress
SKU: HY-19268
Availability: PreOrder

(Synonyms: GW 1818)

GG-818 (GW 1818) is a potent and selective α1 adrenoceptor antagonist, with pK_i values of 9.7 for α1_a, 7.8 for α1_b, and 7.6 for α1_d. GG-818 (GW 1818) can be used for benign prostatic hyperplasia research.

For research use only. We do not sell to patients.

CAS No.: 179535-60-5
Formula: C₂₆H₂₉F₄N₃O₅S
Molecular Weight:571.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

GG-818 Chemical Structure

CAS No.: 179535-60-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

Alpha-1A adrenergic receptor

9.7 (pKi)

Alpha-1B adrenergic receptor

7.8 (pKi)

Alpha-1D adrenergic receptor

7.6 (pKi)

All Adrenergic Receptor Isoforms :

Chemical Information

CAS No. 179535-60-5
Molecular Weight 571.58
Formula C₂₆H₂₉F₄N₃O₅S
SMILES

O=S(C1=CC(CCN2CCC(C3=NC(COCC(F)(F)F)=C(C4=CC=C(F)C=C4)O3)CC2)=CC=C1OC)(N)=O
Synonyms

GW 1818
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kenny B, et al. Pharmacological options in the treatment of benign prostatic hyperplasia. J Med Chem. 1997 Apr 25;40(9):1293-315. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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GG-818

All Adrenergic Receptor Isoforms