179535-60-5
179535-60-5
Chemical Structure
GG-818
Synonym(s): GW 1818
- CAS 番号: 179535-60-5
- Formula:C26H29F4N3O5S
- Molecular Weight:571.58
IUPAC Name: 5-(2-(4-(5-(4-fluorophenyl)-4-((2,2,2-trifluoroethoxy)methyl)oxazol-2-yl)piperidin-1-yl)ethyl)-2-methoxybenzenesulfonamide
InChIKey: AYXYFVWLDFTBIK-UHFFFAOYSA-N
SMILES: O=S(C1=CC(CCN2CCC(C3=NC(COCC(F)(F)F)=C(C4=CC=C(F)C=C4)O3)CC2)=CC=C1OC)(N)=O
Biological Activity: GG-818 (GW 1818) is a potent and selective α1 adrenoceptor antagonist, with pKi values of 9.7 for α1a, 7.8 for α1b, and 7.6 for α1d. GG-818 (GW 1818) can be used for benign prostatic hyperplasia research[1].
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GG-818 | GG-818 (GW 1818) is a potent and selective α1 adrenoceptor antagonist, with pKi values of 9.7 for α1a, 7.8 for α1b, and 7.6 for α1d. GG-818 (GW 1818) can be used for benign prostatic hyperplasia research. | |||||||||||||||||||||
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