H-Glu(Met-OH)-OH
Based on 1 Customer Validation
H-Glu(Met-OH)-OH (H-γ-Glu-Met-OH; γ-Glu-Met) is a DPP-IV inhibitor with an IC50 of 2.11 mM. H-Glu(Met-OH)-OH binds to DPP-IV’s active site to block substrate binding. H-Glu(Met-OH)-OH can be used for the research of type 2 diabetes.
For research use only. We do not sell to patients.
- Purity: 99.63%
- CAS No.: 17663-87-5
- Formula: C10H18N2O5S
- Molecular Weight:278.33
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
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Bioactive Compound Library
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Metabolism/Protease Compound Library
HY-L012
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Anti-diabetic Compound Library
HY-L040
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Peptide Library
HY-L105
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Human Metabolite Library
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Protease Inhibitor Library
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Amino Acid Metabolism Compound Library
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Mass Spectrometry Human Metabolite Library
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Dipeptide Compound Library
HY-L255
Biological Activity
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DPP-4 2.11 mM (IC50) |
H-Glu(Met-OH)-OH (0.0125-2.5 mg/mL; 30 mins) potently inhibits human DPP-IV in a competitive manner with an IC50 of 2.11 mM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 17663-87-5
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Appearance Solid
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Molecular Weight 278.33
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Formula C10H18N2O5S
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Color White to off-white
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Synonyms
H-γ-Glu-Met-OH; γ-Glu-Met
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 10 mg/mL (35.93 mM; Need ultrasonic)
DMSO : 5 mg/mL (17.96 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 3.5929 mL | 17.9643 mL | 35.9286 mL | 89.8214 mL |
| 5 mM | 0.7186 mL | 3.5929 mL | 7.1857 mL | 17.9643 mL | |
| 10 mM | 0.3593 mL | 1.7964 mL | 3.5929 mL | 8.9821 mL | |
| 15 mM | 0.2395 mL | 1.1976 mL | 2.3952 mL | 5.9881 mL | |
| H2O | 20 mM | 0.1796 mL | 0.8982 mL | 1.7964 mL | 4.4911 mL |
| 25 mM | 0.1437 mL | 0.7186 mL | 1.4371 mL | 3.5929 mL | |
| 30 mM | 0.1198 mL | 0.5988 mL | 1.1976 mL | 2.9940 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
H-Glu(Met-OH)-OH Related Classifications
HY-145779 Related Classifications
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