H-HoArg-OH-d4
Based on 1 Customer Validation
H-HoArg-OH-d4 (L-Homoarginine-d4) is the d4-labeled H-HoArg-OH (HY-W008385). H-HoArg-OH (L-Homoarginine) is an orally active endogenous non-protein amino acid. H-HoArg-OH acts as a weak alternative substrate for NOS and interferes with NO production, selectively inhibits tissue-nonspecific alkaline phosphatase (TNAP), and suppresses the uptake of arginine by y+-type transporters (system y+). H-HoArg-OH increases tissue hArg concentrations in vivo, regulates amino acid homeostasis, and improves renal function and pathological features of diabetic nephropathy. H-HoArg-OH can be used in studies related to diabetes and cardiomyopathy.
For research use only. We do not sell to patients.
- CAS No.: 1332075-41-8
- Formula: C7H12D4N4O2
- Molecular Weight:192.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1332075-41-8
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Unlabeled CAS 1483-01-8
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Molecular Weight 192.25
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Formula C7H12D4N4O2
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SMILES
OC([C@@H](N)CC([2H])([2H])C([2H])([2H])CNC(N)=N)=O
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Synonyms
L-Homoarginine-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- H-HoArg-OH-d4
- 1332075-41-8
- L-Homoarginine-d4
- Isotope-Labeled Compounds
- Endogenous Metabolite
- Monocarboxylate Transporter
- Phosphatase
- AGAT
- diabetic nephropathy
- CCK receptor
- pancreatic beta cells
- serum alkaline phosphatase
- Sprague-Dawley rats
- lysine transporter
- takotsubo cardiomyopathy
- Ins2Akita mice
- nitric oxide synthase
- Inhibitor
- inhibitor
- inhibit