2. Neuronal Signaling
  3. Cholinesterase (ChE) Tau Protein
  4. hAChE-IN-2

hAChE-IN-2 is a potent hAChE inhibitor, with an IC50 of 0.71 μM. hAChE-IN-2 can also inhibits tau-oligomerization, with an EC50 of 2.21 μM. hAChE-IN-2 exhibits neuroprotective activity.

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hAChE-IN-2

hAChE-IN-2 Estructura química

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hAChE-IN-2 Related Antibodies

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Descripciòn

hAChE-IN-2 is a potent hAChE inhibitor, with an IC50 of 0.71 μM. hAChE-IN-2 can also inhibits tau-oligomerization, with an EC50 of 2.21 μM. hAChE-IN-2 exhibits neuroprotective activity[1].

IC50 & Target[1]

hAChE

0.71 μM (IC50)

In Vitro

hAChE-IN-2 (compound 21) (1-10 μM) shows neuroprotective activity in SH-SY5Y cells transfected with WT tau[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

hAChE-IN-2 Related Antibodies
Peso molecular

394.44

Fòrmula

C22H23FN4O2
SMILES

COC1=CC=CC(C(N2CCN(CC2)C3=CN=CC=N3)C4=CC=C(C=C4)F)=C1O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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hAChE-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hAChE-IN-2Cholinesterase (ChE)Tau ProteinhAChEtauoligomerizationneuroprotectiveInhibitorinhibitorinhibit

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Nombre del producto:
hAChE-IN-2
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HY-149237
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