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Cat. No.: HY-147555

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HIV-1 inhibitor-38

HIV-1 inhibitor-38 (Compound 91) is a potent HIV-1. HIV-1 inhibitor-38 has the potential for further development as novel latency reversing agents.

For research use only. We do not sell to patients.

CAS No.: 2416971-48-5
Formula: C₁₅H₁₃Cl₃N₆
Molecular Weight:383.66

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

HIV-1 inhibitor-38 Chemical Structure

CAS No.: 2416971-48-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

HIV-1 inhibitor-38 (Compound 91) is a potent HIV-1. HIV-1 inhibitor-38 has the potential for further development as novel latency reversing agents^[1].

All HIV Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	CC₅₀	0.04 μM Compound: 91	Cytotoxicity against human HepG2 cells assessed as growth incubation incubated for 48 hrs by cell titer glo assay Cytotoxicity against human HepG2 cells assessed as growth incubation incubated for 48 hrs by cell titer glo assay	[PMID: 32251744]

Chemical Information

CAS No. 2416971-48-5
Molecular Weight 383.66
Formula C₁₅H₁₃Cl₃N₆
SMILES

ClC1=CC2=C(NC(N3CCN(CC3)C4=CN=C(C(Cl)=C4)Cl)=N2)N=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Nguyen W, et al. Optimization of 5-substituted thiazolyl ureas and 6-substituted imidazopyridines as potential HIV-1 latency reversing agents. Eur J Med Chem. 2020 Jun 1;195:112254. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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HIV-1 inhibitor-38

All HIV Isoforms