HIV-1 inhibitor-78
HIV-1 inhibitor-78 (compound 15f) is a potent and broad-spectrum non-nucleoside reverse transcriptase inhibitor, with an EC50 of 3 nM for wild-type HIV-1. HIV-1 inhibitor-78 can be used for the research of HIV infection.
For research use only. We do not sell to patients.
- Formula: C32H34N6O4S
- Molecular Weight:598.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 598.72
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Formula C32H34N6O4S
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SMILES
CC1=CC(C2=CC=C(C=C2)C#N)=CC(C)=C1OC3=C(C=NC(NC4CCN(CC4)CC5=CC=C(C=C5)S(N)(=O)=O)=N3)CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Huang WJ, et, al. Expanding the Solvent/Protein Region Occupation of the Non-Nucleoside Reverse Transcriptase Inhibitor Binding Pocket for Improved Broad-Spectrum Anti-HIV-1 Efficacy: from Rigid Phenyl-Diarylpyrimidines to Flexible Hydrophilic Piperidine-Diarylpyrimidines. J Med Chem. 2024 Nov 14;67(21):19889-19904. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)