Human Papillomavirus (HPV) E7 protein (49-57)
Based on 1 Customer Validation
Human Papillomavirus (HPV) E7 protein (49-57) is a cytotoxic T lymphocyte (CTL) epitope peptide derived from HPV16 E7 protein (sequence: RAHYNIVTF). Human Papillomavirus (HPV) E7 protein (49-57) induces E749-57-specific CTL responses. Human Papillomavirus (HPV) E7 protein (49-57) can be used for the research of cervical cancer.
For research use only. We do not sell to patients.
- Purity: 98.30%
- CAS No.: 151812-18-9
- Formula: C52H77N15O13
- Molecular Weight:1120.26
-
Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Human Papillomavirus (HPV) E7 protein (49-57) (100 μg/mL; 5 days) promotes the growth of red blood cell-free splenocytes of mice[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:red blood cell-free splenocytes of mice
-
Concentration:100 μg/mL
-
Incubation Time:5 days
-
Result:Promoted the growth of the cell.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:C57BL/6 (6- to 8-week-old female; subcutaneous injection of 5×105 TC-1 cells)[1]
-
Dosage:50 μg; 50 μg (admixed with poly(I:C))
-
Administration:i.p.; on days 5, 9, and 14
-
Result:Showed no significant in vivo anti-tumor efficacy, with tumor growth and survival similar to control groups (standalone treatment).
Inhibited tumor growth, with mean tumor volume reaching ~3500 mm3 by day 33, and significantly prolonged survival compared to control groups (admixed with poly(I:C)).
Chemical Information
-
CAS No. 151812-18-9
-
Appearance Solid
-
Molecular Weight 1120.26
-
Formula C52H77N15O13
-
Color White to off-white
-
Sequence
Arg-Ala-His-Tyr-Asn-Ile-Val-Thr-Phe
-
Sequence Shortening
RAHYNIVTF
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 25 mg/mL (22.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (273 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8926 mL | 4.4632 mL | 8.9265 mL | 22.3162 mL |
| 5 mM | 0.1785 mL | 0.8926 mL | 1.7853 mL | 4.4632 mL | |
| 10 mM | 0.0893 mL | 0.4463 mL | 0.8926 mL | 2.2316 mL | |
| 15 mM | 0.0595 mL | 0.2975 mL | 0.5951 mL | 1.4877 mL | |
| 20 mM | 0.0446 mL | 0.2232 mL | 0.4463 mL | 1.1158 mL |
Human Papillomavirus (HPV) E7 protein (49-57) Related Classifications
HY-P1907 Related Classifications
Powered by Bioz