Indomethacin sodium
Based on 77 publication(s) in Google Scholar
Indomethacin (Indometacin) sodium is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium has anticancer activity and anti-infective activity. Indomethacin sodium can be used for cancer, inflammation and viral infection research..
For research use only. We do not sell to patients.
- CAS No.: 7681-54-1
- Formula: C19H15ClNNaO4
- Molecular Weight:379.77
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Publications Citing Use of MedChemExpress (MCE) Indomethacin sodium
More- Immunity. 2025 Apr 8:S1074-7613(25)00128-1. [Abstract]
- Hepatology. 2023 Feb 1;77(2):456-465. [Abstract]
- Nat Commun. 2025 Oct 2;16(1):8779. [Abstract]
- J Extracell Vesicles. 2024 Dec;13(12):e70025. [Abstract]
- J Extracell Vesicles. 2024 Apr;13(4):e12426. [Abstract]
- Adv Sci (Weinh). 2025 Dec 19:e08956. [Abstract]
- Adv Sci (Weinh). 2024 Dec 5:e2410360. [Abstract]
- Chem Eng J. 2026 Mar 12.
- J Adv Res. 2025 Dec 11:S2090-1232(25)00994-4. [Abstract]
- Biomaterials. 2022 Oct:289:121800. [Abstract]
- Phytomedicine. 2025 Oct 11:148:157400. [Abstract]
- Phytomedicine. 2022 Apr:98:153928. [Abstract]
- Phytomedicine. 2021 Nov:92:153751. [Abstract]
- Int Endod J. 2024 Sep;57(9):1228-1246. [Abstract]
- Chem Mater. 2017, 29(19):8221-8238.
- Appl Mater Today. 2023 Apr.
- Clin Transl Med. 2021 Oct;11(10):e548. [Abstract]
- J Med Chem. 2021 Mar 11;64(5):2725-2738. [Abstract]
- Antioxidants (Basel). 2021 Aug 24;10(9):1333. [Abstract]
- Int J Nanomedicine. 2020 May 1;15:3087-3098. [Abstract]
- Phytother Res. 2025 Oct;39(10):4704-4717. [Abstract]
- Ecotoxicol Environ Saf. 2025 Nov 15:307:119433. [Abstract]
- Ecotoxicol Environ Saf. 2025 Jan 22:290:117765. [Abstract]
- Eur J Med Chem. 2023 Oct 5:258:115602. [Abstract]
- Eur J Med Chem. 2021 Dec 5:225:113743. [Abstract]
- Chin Med. 2023 Sep 7;18(1):113. [Abstract]
- Pharmaceutics. 2024 May 29;16(6):731. [Abstract]
- J Ethnopharmacol. 2024 Aug 7:118660. [Abstract]
- World J Gastroenterol. 2023 Oct 21;29(39):5452-5470. [Abstract]
- Inflammopharmacology. 2025 Dec 2. [Abstract]
- J Mol Liq. 2026 May 23;457:129686.
- Cells. 2026 Feb 11;15(4):329. [Abstract]
- Int J Pharm. 2017 Jan 30;517(1-2):19-24. [Abstract]
- Life Sci. 2026 Mar 15:389:124236. [Abstract]
- Drug Des Devel Ther. 2025 Mar 19:19:2035-2050. [Abstract]
- Chin J Nat Med. 2021 Oct;19(10):741-749. [Abstract]
- Eur J Pharm Sci. 2023 Oct 1:189:106550. [Abstract]
- ACS Appl Bio Mater. 2023 Jul 17;6(7):2816-2825. [Abstract]
- Bioorg Chem. 2022 Dec:129:106206. [Abstract]
- Mol Pharm. 2025 Aug 4;22(8):4969-4982. [Abstract]
- Cell Rep Methods. 2023 Oct 23;3(10):100599. [Abstract]
- J Lipid Res. 2026 Feb;67(2):100981. [Abstract]
- Drug Metab Dispos. 2025 Nov 10;53(12):100200. [Abstract]
- Langmuir. 2020 Sep 29;36(38):11374-11382. [Abstract]
- Food Sci Nutr. 2026 Jan 7;14(1):e71429. [Abstract]
- Metabolites. 2025 May 14;15(5):324. [Abstract]
- Biotechnol Bioeng. 2021 Dec;118(12):4687-4698. [Abstract]
- Mol Med Rep. 2023 Sep;28(3):164. [Abstract]
- Front Med. 2021 Apr 13:8:634882. [Abstract]
- Andrology. 2024 May 22. [Abstract]
- Front Physiol. 2021 Oct 28;12:770430. [Abstract]
- BMC Cancer. 2019 Dec 2;19(1):1166. [Abstract]
- Toxicol Appl Pharmacol. 2017 May 15:323:44-52. [Abstract]
- Biochim Biophys Acta Mol Cell Biol Lipids. 2025 Jul 7;1870(6):159659. [Abstract]
- Cell Transplant. 2025 Jan-Dec:34:9636897251376125. [Abstract]
- Int J Med Sci. 2025 Mar 10;22(8):1773-1790. [Abstract]
- Am J Physiol Endocrinol Metab. 2024 May 1;326(5):E696-E708. [Abstract]
- J Therm Biol. 2024 Jul 2:123:103906. [Abstract]
- Organogenesis. 2025 Dec;21(1):2460261. [Abstract]
- J Appl Toxicol. 2024 Oct;44(10):1528-1539. [Abstract]
- Immun Inflamm Dis. 2023 Feb;11(2):e787. [Abstract]
- Clin Exp Pharmacol Physiol. 2025 Nov;52(11):e70081. [Abstract]
- BMC Nephrol. 2024 Jul 15;25(1):226. [Abstract]
- FEBS Open Bio. 2025 Jan;15(1):122-139. [Abstract]
- Biomed Res Int. 2021 May 14:2021:5565748. [Abstract]
- Biochem Biophys Res Commun. 2025 Aug 27:781:152551. [Abstract]
- Biochem Biophys Res Commun. 2025 Jul 1:768:151920. [Abstract]
- Thai Journal of Pharmaceutical Sciences. 2025 Dec.
- Res Sq. 2025 Oct 27.
- Res Sq. 2025 Nov 12.
- bioRxiv. 2025 Jul 12:2025.07.08.663754. [Abstract]
- bioRxiv. 2025 Jun 3:2025.06.01.657218. [Abstract]
- SSRN. 2025 Mar 31.
- bioRxiv. 2024 Nov 08.
- Eur Rev Med Pharmacol Sci. 2020 Nov;24(21):11199-11211. [Abstract]
- Research Square Preprint. 2020 Oct.
- Patent. US20180263995A1.
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Biological Activity
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COX-1 18 nM (IC50) |
COX-2 26 nM (IC50) |
Indomethacin (Indometacin) sodium (0-150 μM; 24 hours; 3LL-D122 cells) has anticancer activity in vitro[2].
Indomethacin (Indometacin) sodium (0-1000 μM) protects the host cells from damage caused by the virus through activates PKR, resulting in elF2α phosphorylation, and in turn shutting of translation of viral protein and inhibiting replication of the virus (IC50=2μM)[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:3LL-D122 cells (highly metastatic variant of mouse LLcarcinoma cells)
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Concentration:0, 20, 50, 100 and 150 μM
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Incubation Time:24 hours
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Result:Inhibited cell viability at 20 mM, with 50% inhibition at 60 nM.
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Cell Line:3LL-D122 cells (highly metastatic variant of mouse LLcarcinoma cells)
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Concentration:0, 30 and 80 μM
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Incubation Time:24 hours
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Result:Decreased in the percentage of cells at the G2/M phase and increased in the percentage of cells at G1 phase.
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Animal Model:Male Sprague-Dawley rats[1]
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Dosage:0.01-10 mg/kg
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Administration:Oral administration; for 3 hours
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Result:Inhibited the carrageenan-induced rat paw oedema (ED50=2.0 mg/kg) and hyperalgesia (ED50=1.5 mg/kg) in a dose-dependent manner.
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Animal Model:Male C57BL/6J mice[2]
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Dosage:10 mg/mL
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Administration:Oral administration; daily, for 29 days
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Result:Delayed the onset of tumor growth and the initial growth rate of the footpad tumors.
Please do not refer to only one article to determine the experimental conditions. It is recommended to determine the optimal experimental conditions (animal strain, age, dosage, frequency and cycle, detection time and indicators, etc.) through preliminary experiments before the formal experiment.
Indomethacin can be used to induce gastric ulcer models. After oral administration, the drug is absorbed rapidly and completely, although there are interindividual and intraindividual variations. Typically, the plasma peak concentration (2-3 μg/mL) is reached within 1-2 hours. However, coadministration with food reduces and delays the peak concentration without affecting the total absorption. At therapeutic concentrations, 90% of Indomethacin is bound to albumin in the plasma[4].
Administration: 100 mg/kg • p.o. • single dose
(2) Indomethacin were dissolved in saline with 5% NaOH.
Histopathological changes: Showed severe erosion of the mucosa, reaching down to the lamina muscularis; observed hemorrhagic infiltration, edema in the submucosa, and severe hyperemia of the vessels.
Molecular changes: Showed intense Tnf-α expression.
Biochemical changes: Increased MDA, TOS levels, reduced TAS levels, CAT and GPx activities and GSH levels.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 7681-54-1
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Molecular Weight 379.77
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Formula C19H15ClNNaO4
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SMILES
O=C(O[Na])CC1=C(C)N(C(C2=CC=C(Cl)C=C2)=O)C3=C1C=C(OC)C=C3
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Synonyms
INDOMETHACIN SODIUM
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (77)
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Journal Impact Factor
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Most Recent
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Immunity
Alcaligenes faecalis induces intestinal T helper-17 cells by enhancing Rorc transcription through E3 ligase Trim21-mediated Fbxw7 degradation. [Abstract]2025 Apr 8:S1074-7613(25)00128-1. PMID: 40215968 -
Hepatology
Eosinophils protect against acetaminophen-induced liver injury through cyclooxygenase-mediated IL-4/IL-13 production. [Abstract]2023 Feb 1;77(2):456-465. PMID: 35714036
Indomethacin sodium purchased from MedChemExpress. Usage Cited in: Hepatology. 2023 Feb 1;77(2):456-465. [Abstract]
WT BmEos was treated with IL-33 (20 ng/ml) in the presence or absence of indomethacin (50 μM) for 24 h. Protein levels of IL-4 and IL-13 in the supernatants were measured by ELISA.
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Nat Commun
2025 Oct 2;16(1):8779. PMID: 41038808 -
J Extracell Vesicles
CD7-targeting pro-apoptotic extracellular vesicles: A novel approach for T-cell haematological malignancy therapy. [Abstract]2024 Dec;13(12):e70025. PMID: 39676736 -
J Extracell Vesicles
Proton pump inhibitors enhance macropinocytosis-mediated extracellular vesicle endocytosis by inducing membrane v-ATPase assembly. [Abstract]2024 Apr;13(4):e12426. PMID: 38532609 -
Adv Sci (Weinh)
Exclusive Breastfeeding Drives AMPK-Dependent Thermogenic Memory in BAT and Promotes Long-Term Metabolic Benefits in Offspring. [Abstract]2025 Dec 19:e08956. PMID: 41417620 -
Adv Sci (Weinh)
Targeted SPP1 Inhibition of Tumor-Associated Myeloid Cells Effectively Decreases Tumor Sizes. [Abstract]2024 Dec 5:e2410360. PMID: 39639496 -
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J Adv Res
High-throughput screening identifies FDA approved drug mitiglinide as a novel pyroptosis inhibitor and therapeutic agent for osteoarthritis. [Abstract]2025 Dec 11:S2090-1232(25)00994-4. PMID: 41386507 -
Biomaterials
2022 Oct:289:121800. PMID: 36166893 -
Phytomedicine
Perillyl alcohol ameliorates high-fat diet-induced obesity in mice by modulating gut microbiota and activating IRF4-mediated brown fat thermogenesis. [Abstract]2025 Oct 11:148:157400. PMID: 41138577 -
Phytomedicine
Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways. [Abstract]2022 Apr:98:153928. PMID: 35104760 -
Phytomedicine
3'-Oxo-tabernaelegantine A (OTNA) selectively relaxes pulmonary arteries by inhibiting AhR. [Abstract]2021 Nov:92:153751. PMID: 34563984 -
Int Endod J
Integration of single-cell RNA sequencing of endothelial cells and proteomics to unravel the role of ICAM1-PTGS2 communication in apical periodontitis: A laboratory investigation. [Abstract]2024 Sep;57(9):1228-1246. PMID: 38713190 -
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Clin Transl Med
Targeting integrin αvβ3 with indomethacin inhibits patient-derived xenograft tumour growth and recurrence in oesophageal squamous cell carcinoma. [Abstract]2021 Oct;11(10):e548. PMID: 34709754
Indomethacin sodium purchased from MedChemExpress. Usage Cited in: Clin Transl Med. 2021 Oct;11(10):e548. [Abstract]
ITGAV, ITGB3, p-FAK, FAK, p-PI3K, PI3K, p-AKT, AKT, p-GSK3β, and GSK3β protein levels were assessed in KYSE30 cells by Western blotting after treatment with DMSO or 200 µM Indomethacin (0–96 h).
Indomethacin sodium purchased from MedChemExpress. Usage Cited in: Clin Transl Med. 2021 Oct;11(10):e548. [Abstract]
HEK-293T cells were co-transfected with FLAG-ITGAV and HA-ubiquitin plasmids, pre-treated with MG132 for 12 h, and then incubated with indomethacin (200 µM) for 2 days.
Indomethacin sodium purchased from MedChemExpress. Usage Cited in: Clin Transl Med. 2021 Oct;11(10):e548. [Abstract]
KYSE30 and KYSE510 cells were treated with DMSO or Indomethacin for 24 h, followed by the detection of ITGAV protein levels using immunofluorescence.
Indomethacin sodium purchased from MedChemExpress. Usage Cited in: Clin Transl Med. 2021 Oct;11(10):e548. [Abstract]
ESCC cells were treated with DMSO or different concentrations of Indomethacin for various times (24, 48, or 96 h). Cell growth inhibition was detected by MTT assay.
Indomethacin sodium purchased from MedChemExpress. Usage Cited in: Clin Transl Med. 2021 Oct;11(10):e548. [Abstract]
PDX tumour size was plotted over 41 days (LEG74, n = 8/group), 26 days (LEG92, n = 12/group), or 13 days (LEG84, n = 10/group) to assess the effect of Indomethacin. Vehicle or indomethacin (1 or 4 mg/kg) was administered intra-gastrically. Tumour volumes were measured twice per week.
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J Med Chem
Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration. [Abstract]2021 Mar 11;64(5):2725-2738. PMID: 33619967 -
Antioxidants (Basel)
Discovery of Novel Pterostilbene Derivatives That Might Treat Sepsis by Attenuating Oxidative Stress and Inflammation through Modulation of MAPKs/NF-κB Signaling Pathways. [Abstract]2021 Aug 24;10(9):1333. PMID: 34572964 -
Int J Nanomedicine
A Mansonone Derivative Coupled with Monoclonal Antibody 4D5-Modified Chitosan Inhibit AKR1C3 to Treat Castration-Resistant Prostate Cancer. [Abstract]2020 May 1;15:3087-3098. PMID: 32431503 -
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Daidzin Inhibits Endoplasmic Reticulum Stress by Regulating FoxO1 Expression to Alleviate Osteoarthritis Progression. [Abstract]2025 Oct;39(10):4704-4717. PMID: 40889796 -
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PPARγ-responsive luciferase reporter system for high-throughput screening of chemical toxins with potential pulmonary fibrosis effects. [Abstract]2025 Nov 15:307:119433. PMID: 41273832 -
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Eur J Med Chem
Novel pterostilbene derivatives ameliorate heart failure by reducing oxidative stress and inflammation through regulating Nrf2/NF-κB signaling pathway. [Abstract]2023 Oct 5:258:115602. PMID: 37406380 -
Eur J Med Chem
Design, synthesis, and SAR study of novel 4,5-dihydropyrazole-Thiazole derivatives with anti-inflammatory activities for the treatment of sepsis. [Abstract]2021 Dec 5:225:113743. PMID: 34403978 -
Chin Med
Ajugol's upregulation of TFEB-mediated autophagy alleviates endoplasmic reticulum stress in chondrocytes and retards osteoarthritis progression in a mouse model. [Abstract]2023 Sep 7;18(1):113. PMID: 37679844 -
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J Ethnopharmacol
Lycopodium japonicum Thunb. inhibits chondrocyte apoptosis, senescence and inflammation in osteoarthritis through STING/NF-κB signaling pathway. [Abstract]2024 Aug 7:118660. PMID: 39121926 -
World J Gastroenterol
Prostaglandin F2α synthase promotes oxaliplatin resistance in colorectal cancer through prostaglandin F2α-dependent and F2α-independent mechanism. [Abstract]2023 Oct 21;29(39):5452-5470. PMID: 37900995 -
Inflammopharmacology
The sesquiterpene lactone components of Cichorium glandulosum suppress both in vitro and in vivo inflammatory responses by reducing IL-1β levels. [Abstract]2025 Dec 2. PMID: 41329398 -
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Cells
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Network Pharmacology and Experimental Validation Reveal Sishen Pill's Efficacy in Treating NSAID-Induced Small Intestinal Ulcers. [Abstract]2025 Mar 19:19:2035-2050. PMID: 40124554 -
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Eur J Pharm Sci
Biophysical and docking study on the interaction of anticancer drugs encorafenib and binimetinib with human serum albumin. [Abstract]2023 Oct 1:189:106550. PMID: 37527692 -
ACS Appl Bio Mater
Feedback-Elevated Antitumor Amplifier of Self-Delivery Nanomedicine by Suppressing Photodynamic Therapy-Caused Inflammation. [Abstract]2023 Jul 17;6(7):2816-2825. PMID: 37326439 -
Bioorg Chem
Discovery of novel dihydropyrazole-stilbene derivatives for ameliorating heart failure through modulation of p38/NF-κB signaling pathway. [Abstract]2022 Dec:129:106206. PMID: 36288667 -
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RECOVER identifies synergistic drug combinations in vitro through sequential model optimization. [Abstract]2023 Oct 23;3(10):100599. PMID: 37797618 -
J Lipid Res
2026 Feb;67(2):100981. PMID: 41565113 -
Drug Metab Dispos
Application of acoustic ejection mass spectrometry for plasma protein binding assay using flux dialysis. [Abstract]2025 Nov 10;53(12):100200. PMID: 41386030 -
Langmuir
2020 Sep 29;36(38):11374-11382. PMID: 32902993 -
Food Sci Nutr
Anti-Diabetic Effects of Ayanin, a Flavonoid Compound, in STZ/HFD-Induced Diabetic Mice by Upregulating GLUT4 and Suppressing Macrophage-Driven Inflammation in Adipose Tissues. [Abstract]2026 Jan 7;14(1):e71429. PMID: 41509193 -
Metabolites
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Biotechnol Bioeng
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Front Med
Erythropoietin Attenuates Experimental Contrast-Induced Nephrology: A Role for the Janus Kinase 2/Signal Transducer and Activator of Transcription 3 Signaling Pathway. [Abstract]2021 Apr 13:8:634882. PMID: 33928100 -
Andrology
Cellular mechanism underlying leptin-induced anion secretion of rat epididymal epithelial cells. [Abstract]2024 May 22. PMID: 38778669 -
Front Physiol
Roles of Endothelial Motilin Receptor and Its Signal Transduction Pathway in Motilin-Induced Left Gastric Artery Relaxation in Dogs. [Abstract]2021 Oct 28;12:770430. PMID: 34777026 -
BMC Cancer
PPARα ligand, AVE8134, and cyclooxygenase inhibitor therapy synergistically suppress lung cancer growth and metastasis. [Abstract]2019 Dec 2;19(1):1166. PMID: 31791289 -
Toxicol Appl Pharmacol
2017 May 15:323:44-52. PMID: 28341536 -
Biochim Biophys Acta Mol Cell Biol Lipids
Partial inhibition of adipose CIDEC improves insulin sensitivity and increases energy expenditure in high-fat diet-fed mice via activating ATGL-PPARα pathway. [Abstract]2025 Jul 7;1870(6):159659. PMID: 40633832 -
Cell Transplant
Adipose-derived stem cells inhibit dendritic cell migration by secreting tumor necrosis factor-α-stimulated gene 6 to improve the allogeneic skin transplantation survival rate in mice. [Abstract]2025 Jan-Dec:34:9636897251376125. PMID: 41108126 -
Int J Med Sci
Integrated Phenotypic and Transcriptomic Analyses of Osteoporosis in Type 2 Diabetic Mice. [Abstract]2025 Mar 10;22(8):1773-1790. PMID: 40225857 -
Am J Physiol Endocrinol Metab
Glycogen synthesis is required for adaptive thermogenesis in beige adipose tissue and affects diet-induced obesity. [Abstract]2024 May 1;326(5):E696-E708. PMID: 38568151 -
J Therm Biol
Differential expression of ADRB1 causes different responses to norepinephrine in adipocytes of Duroc-Landrace-Yorkshire pigs and min pigs. [Abstract]2024 Jul 2:123:103906. PMID: 38970835 -
Organogenesis
Tetramethylpyrazine Confers Protection Against Oxidative Stress and NLRP3-Dependent Pyroptosis in Rats with Endometriosis. [Abstract]2025 Dec;21(1):2460261. PMID: 39967390 -
J Appl Toxicol
Differential impacts of nonsteroidal anti-inflammatory drugs on lifespan and healthspan in aged Caenorhabditis elegans. [Abstract]2024 Oct;44(10):1528-1539. PMID: 38840409 -
Immun Inflamm Dis
Limonin ameliorates indomethacin-induced intestinal damage and ulcers through Nrf2/ARE pathway. [Abstract]2023 Feb;11(2):e787. PMID: 36840501 -
Clin Exp Pharmacol Physiol
Indole-3-Propionic Acid Improves Vascular Function in High-Fat Diet-Induced Obese Mice via eNOS. [Abstract]2025 Nov;52(11):e70081. PMID: 41057979 -
BMC Nephrol
Sodium selenite attenuates inflammatory response and oxidative stress injury by regulating the Nrf2/ARE pathway in contrast-induced acute kidney injury in rats. [Abstract]2024 Jul 15;25(1):226. PMID: 39009991 -
FEBS Open Bio
Anti-inflammatory properties of ophioglonin derived from the fern Ophioglossum vulgatum L. via inactivating NF-κB and MAPK signaling pathways. [Abstract]2025 Jan;15(1):122-139. PMID: 39455284 -
Biomed Res Int
Gentiopicroside Produces Endothelium-Independent Vasodilation by Deactivating the PI3K/Akt/Rho-Kinase Pathway in Isolated Rat Thoracic Aorta. [Abstract]2021 May 14:2021:5565748. PMID: 34095301 -
Biochem Biophys Res Commun
The synergistic administration of sanguinarine and curcumin ameliorates indomethacin-induced small intestinal injury in rats through the modulation of Nrf2 and NF-κB signaling pathways. [Abstract]2025 Aug 27:781:152551. PMID: 40885044 -
Biochem Biophys Res Commun
Exosomes derived from human umbilical cord mesenchymal stem cells can reverse ventricular remodeling and improve long-term cardiac function after acute myocardial infarction. [Abstract]2025 Jul 1:768:151920. PMID: 40327908 -
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bioRxiv
2025 Jul 12:2025.07.08.663754. PMID: 40672312 -
bioRxiv
A genetically encoded fluorescent sensor for monitoring spatiotemporal prostaglandin E2 dynamics in vivo. [Abstract]2025 Jun 3:2025.06.01.657218. PMID: 40501671 -
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Eur Rev Med Pharmacol Sci
MSCs reduce airway remodeling in the lungs of asthmatic rats through the Wnt/β-catenin signaling pathway. [Abstract]2020 Nov;24(21):11199-11211. PMID: 33215438 -
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Purity & Documentation
References
[1]. Riendeau D, et, al. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. Br J Pharmacol. 1997 May;121(1):105-17. [Content Brief]
[2]. Amici C, et, al. Inhibition of viral protein translation by indomethacin in vesicular stomatitis virus infection: role of eIF2α kinase PKR. Cell Microbiol. 2015 Sep;17(9):1391-404. [Content Brief]
[3]. Eli Y, et, al. Comparative effects of indomethacin on cell proliferation and cell cycle progression in tumor cells grown in vitro and in vivo. Biochem Pharmacol. 2001 Mar 1;61(5):565-71. [Content Brief]
[4]. Helleberg L, et, al. Clinical Pharmacokinetics of indomethacin. Clin Pharmacokinet. 1981 Jul-Aug;6(4):245-58. [Content Brief]
[5]. Sabiu S, et, al. Indomethacin-induced gastric ulceration in rats: Protective roles of Spondias mombin a nd Ficus exasperate. Toxicol Rep. 2015 Jan 8:2:261-267. [Content Brief]
[6]. Danisman B, et, al, Carnosic Acid Ameliorates Indomethacin-Induced Gastric Ulceration in Rats by Alleviating Oxidative Stress and Inflammation. Biomedicines. 2023 Mar 9;11(3):829. [Content Brief]
Calculators
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