Inositol 1,3,4,5-tetraphosphate
Based on 1 publication(s) in Google Scholar
Inositol 1,3,4,5-tetraphosphate is an inositol tetraphosphate. Inositol 1,3,4,5-tetraphosphate is metabolically produced from Ins (1,4,5) P3 via 3-kinase, participates in intracellular signal transduction systems, and elevates intracellular calcium concentrations when present.
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- CAS No.: 102850-29-3
- Formula: C6H16O18P4
- Molecular Weight:500.08
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Publications Citing Use of MedChemExpress (MCE) Inositol 1,3,4,5-tetraphosphate
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Biological Activity
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Cell Line
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Type | Value | Description | References |
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| SH-SY5Y | EC50 |
2.1 μM
Compound: Ins(1,3,4,5)P4
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Compound was evaluated for its ability to mobilize calcium from [Ca(2+)]-preloaded SH-SY5Y cells permeabilised using saponin
Compound was evaluated for its ability to mobilize calcium from [Ca(2+)]-preloaded SH-SY5Y cells permeabilised using saponin
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10.1016/S0960-894X(00)80007-4 |
Inositol 1,3,4,5-tetraphosphate is metabolically produced from Ins (1,4,5) P3 via 3-kinase, participates in intracellular signal transduction systems, and increases intracellular calcium concentration when present[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 102850-29-3
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Molecular Weight 500.08
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Formula C6H16O18P4
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SMILES
O(P(=O)(O)O)[C@@H]1[C@@H](OP(=O)(O)O)[C@@H](O)[C@@H](OP(=O)(O)O)[C@H](O)[C@H]1OP(=O)(O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Nat Commun
A clade of receptor-like cytoplasmic kinases and 14-3-3 proteins coordinate inositol hexaphosphate accumulation. [Abstract]2024 Jun 14;15(1):5107. PMID: 38877001
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Inositol 1,3,4,5-tetraphosphate Related Classifications
HY-W127317 Related Classifications
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- Inositol 1,3,4,5-tetraphosphate
- 102850-29-3
- Endogenous Metabolite
- inositol tetraphosphate
- intracellular calcium concentration
- secondary messenger
- inositol phosphate fractions
- calcium ion influx
- naturally fermented cowpeas
- 3-kinase
- Ins(1,4,5)P3
- Vigna sinensis var. Carilla
- intracellular signal transduction systems
- Inhibitor
- inhibitor
- inhibit