CDK9-IN-49
CDK9-IN-49 is a CDK9 inhibitor with an IC50 of 7.32 nM. CDK9-IN-49 inhibits the proliferation of various cancer cells. CDK9-IN-49 can be used in the research of cancers such as acute myeloid leukemia and prostate cancer.
For research use only. We do not sell to patients.
- CAS No.: 2987897-39-0
- Formula: C23H24FN5O2S
- Molecular Weight:453.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CDK9 7.32 nM (IC50) |
CDK9-IN-49 (Example 27) (0.00000256-1 μM, 3 days) potently inhibits the viability of MOLM-13 acute myeloid leukemia cells, LNCaP prostate cancer cells, and MV-4-11 acute myeloid leukemia cells, with IC50 values of 0.428, 0.72, and 1.29 nM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MOLM-13, LNCaP, MV-4-11 cell
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Concentration:0.00000256-1μM, starting with 1 μM, a 5-fold serial dilution was performed to obtain 9 concentrations
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Incubation Time:3 days
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Result:Inhibited MOLM-13 cell viability with an IC50 of 0.428 nM.
Inhibited LNCaP cell viability with an IC50 of 0.72 nM.
Inhibited MV-4-11 cell viability with an IC50 of 1.29 nM.
Chemical Information
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CAS No. 2987897-39-0
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Molecular Weight 453.53
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Formula C23H24FN5O2S
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SMILES
CN1C(C(C)C)=C2C=C(C3=C(F)C=NC(NC4=CC(CS(C)(=O)=O)=CC=N4)=C3)C=CC2=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK9-IN-49 Related Classifications
HY-185340 Related Classifications
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