COL26A1 - collagen type XXVI alpha 1 chain Gene

Also Known as EMI6; EMU2; SH2B; EMID2

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 136227

About COL26A1

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:101,362,388-101,559,024 (from NCBI)

This gene has 3 transcripts (splice variants), 182 orthologues and 37 paralogues. Biased expression in brain (RPKM 3.1), kidney (RPKM 1.3) and 9 other tissues.

Summary

This gene encodes a protein containing an emilin domain and two Collagen stretches. This gene may be associated with aspirin-intolerant asthma. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

COL26A1 Products (2)

mRNA Protein Name
NM_001278563.3 NP_001265492.1 collagen alpha-1(XXVI) chain isoform 1 precursor
NM_133457.5 NP_597714.2 collagen alpha-1(XXVI) chain isoform 2 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

COL26A1 Protein Structure

EMI

EMI: EMI domain (52 - 124)

Collagen

Collagen: Collagen triple helix repeat (20 copies) (203 - 259)

Collagen

Collagen: Collagen triple helix repeat (20 copies) (302 - 359)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 440 a.a.
Protein Preferred Names Protein Names

collagen alpha-1(XXVI) chain

  • EMI domain containing 2

関連疾患

Diseases Alias
Acute Ethmoiditis

  • Acute Ethmoidal Sinusitis

  • Acute Ethmoid Sinusitis

  • Ethmoidal Sinus - Acute
Anal Carcinoma In Situ

  • Carcinoma In Situ Of Anal Canal

  • Carcinoma In Situ Of Anus

  • Anal Carcinoma Stage 0

  • Anal Intraepithelial Neoplasia Grade Iii

  • Intraepithelial Neoplasia Of Anal Canal, High Grade

  • Ain - [Anal Intraepithelial Neoplasia] High Grade
Asthma

  • Chronic Obstructive Asthma

  • Asthma, Diminished Response To Antileukotriene Treatment In

  • Bronchial Hyperreactivity

  • Asthma, Susceptibility To

  • Asthma, Bronchial

  • Asthma, Protection Against

  • Asthma, Nocturnal, Susceptibility To

  • Nocturnal Asthma

  • Asthma-Related Traits

  • Asthma-Related Traits, Susceptibility To

  • Asthma, Nocturnal

  • Chronic Obstructive Asthma With Acute Exacerbation

  • Chronic Obstructive Asthma With Status Asthmaticus

  • Exercise Induced Asthma

  • Exercise-Induced Asthma

  • Bronchial Asthma

  • Asthma, Exercise-Induced

  • Idiosyncratic Asthma

  • Unspecified Asthma With Acute Exacerbation

  • Asthma, Unspecified, With Stated Status Asthmaticus

  • Status Asthmaticus Nos

  • Acute Severe Asthma

  • Acute Severe Bronchial Asthma

  • Status Asthma

  • Status Post Asthmaticus
Asthma, Nasal Polyps, And Aspirin Intolerance

  • Asthma And Nasal Polyps

  • Asa Triad

  • Asthma, Aspirin-Induced, Susceptibility To

  • Asthma, Aspirin-Induced

  • Asthma, With Nasal Polyps And Aspirin Intolerance

  • ANPAI

  • Aia

  • Aspirin-Intolerant Asthma

  • Asthma Aspirin-Induced

  • Nasal Polyps Asthma And Aspirin Sensitivity

  • Samter Triad

  • Asthma With Aspirin Triad Including Nonsteroidal Anti-Inflammatory Activity And Nasal Polyps
Chronic Maxillary Sinusitis

  • Chronic Antritis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS02978 COL26A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Macaca mulatta COL26A1 VGNC VGNC:81293
Felis catus COL26A1 VGNC VGNC:61056
Bos taurus COL26A1 VGNC VGNC:52757
Rattus norvegicus COL26A1 RGD RGD:1591401
Mus musculus COL26A1 MGD MGI:2155345
Others COL26A1 NCBI