Ddb1 - damage-specific DNA binding protein 1 Gene

Enables damaged DNA binding activity. Predicted to be involved in several processes, including cellular protein metabolic process; positive regulation by virus of viral protein levels in host cell; and positive regulation of gluconeogenesis. Predicted to act upstream of or within Wnt signaling pathway; negative regulation of apoptotic process; and proteasomal protein catabolic process. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of Cul4A-RING E3 ubiquitin Ligase complex and Cul4B-RING E3 ubiquitin Ligase complex. Predicted to be active in nucleus and site of double-strand break. Orthologous to human DDB1 (damage specific DNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]