Bccip - BRCA2 and CDKN1A interacting protein Gene

Also Known as TOK-1; 1110013J05Rik

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 66165

Summary

Predicted to enable kinase regulator activity and tubulin binding activity. Involved in cellular response to DNA damage stimulus; microtubule anchoring; and mitotic spindle organization. Located in centrosome and mitotic spindle pole. Is expressed in several structures, including axial musculature; brain ventricular layer; orbito-sphenoid; submandibular gland primordium; and thymus primordium. Orthologous to human BCCIP (BRCA2 and CDKN1A interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Bccip Products (1)

mRNA Protein Name
NM_025392.2 NP_079668.2 BRCA2 and CDKN1A-interacting protein
Biological Process GO Annotation Evidence 参考文献 由来
involved in DNA damage response IMP
IMP: Inferred from mutant phenotype
21966279 MGI
involved in microtubule anchoring IMP
IMP: Inferred from mutant phenotype
28394342 MGI
involved in microtubule cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
28394342 MGI
involved in mitotic spindle organization IMP
IMP: Inferred from mutant phenotype
28394342 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in centrosome IDA
IDA: Inferred from direct assay
28394342 MGI
located in mitotic spindle pole IDA
IDA: Inferred from direct assay
28394342 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BRCA2 and CDKN1A-interacting protein

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Bccip NCBI NCBI:56647