PAPLN - papilin, proteoglycan like sulfated glycoprotein Gene
Also Known as PPN
生物種: Homo sapiens
About PAPLN
This gene has 12 transcripts (splice variants), 265 orthologues and 25 paralogues. Broad expression in spleen (RPKM 9.2), kidney (RPKM 8.9) and 22 other tissues.
Summary
Predicted to enable metalloendopeptidase activity. Predicted to be involved in extracellular matrix organization. Predicted to be located in basement membrane. Predicted to be active in extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]
PAPLN Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001365906.3 | NP_001352835.1 | papilin isoform 2 precursor |
| NM_001365907.2 | NP_001352836.1 | papilin isoform 3 precursor |
| NM_173462.4 | NP_775733.3 | papilin isoform 1 precursor |
PAPLN Protein Structure
TSP_1: Thrombospondin type 1 domain (30 - 79)
ADAM_spacer1: ADAM-TS Spacer 1 (184 - 298)
TSP_1: Thrombospondin type 1 domain (311 - 360)
TSP_1: Thrombospondin type 1 domain (369 - 424)
TSP_1: Thrombospondin type 1 domain (430 - 480)
TSP_1: Thrombospondin type 1 domain (491 - 538)
Kunitz_BPTI: Kunitz/Bovine pancreatic trypsin inhibitor domain (753 - 805)
I-set: Immunoglobulin I-set domain (916 - 992)
I-set: Immunoglobulin I-set domain (1048 - 1129)
I-set: Immunoglobulin I-set domain (1135 - 1219)
PLAC: PLAC (protease and lacunin) domain (1235 - 1268)
- 0
- 200
- 400
- 600
- 800
- 1000
- 1200
- 1278 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
papilin |
|
PAPLN 抗体
| 製品番号 | 製品名 | アプリケーション | 反応性 |
|---|---|---|---|
| HY-P83874 | PAPLN Antibody (YA3571) | WB, ICC/IF, ELISA | Human, Mouse |
| HY-P83874A | PAPLN Antibody (YA3571)(PBS only) | WB, ICC/IF, ELISA | Human, Mouse |
関連疾患
| Diseases | Alias | |
|---|---|---|
| Radial Nerve Lesion |
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| Weill-Marchesani Syndrome |
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| Ehlers-Danlos Syndrome, Dermatosparaxis Type |
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| Radial Neuropathy |
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| Peters-Plus Syndrome |
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| Isolated Ectopia Lentis |
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| Acromicric Dysplasia |
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| Geleophysic Dysplasia |
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| Winchester Syndrome |
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| Intellectual Developmental Disorder, X-Linked 109 |
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| Aortic Aneurysm, Familial Thoracic 1 |
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Orthologs Information
| 生物種 | Symbol | 由来 | ID |
|---|---|---|---|
| Canis familiaris | PAPLN | VGNC | VGNC:49735 |
| Mus musculus | PAPLN | MGD | MGI:2386139 |
| Rattus norvegicus | PAPLN | RGD | RGD:1311176 |
| Felis catus | PAPLN | VGNC | VGNC:64034 |
| Macaca mulatta | PAPLN | VGNC | VGNC:75647 |
| Bos taurus | PAPLN | VGNC | VGNC:32571 |
| Others | PAPLN | NCBI |