441765-97-5
Chemical Structure
Talaglumetad (hydrochloride)
Synonym(s): LY-544344 (hydrochloride)
- CAS No.: 441765-97-5
- Formula:C11H17ClN2O5
- Molecular Weight:292.72
IUPAC Name: (1S,2S,5R,6S)-2-((S)-2-aminopropanamido)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid hydrochloride
InChIKey: TWZDLCLCMKMJPE-OAOSNHGPSA-N
SMILES: O=C([C@@H](N)C)N[C@]([C@@]1([H])[C@]2([H])[C@@H]1C(O)=O)(CC2)C(O)=O.Cl
Biological Activity: Talaglumetad hydrochloride (LY-544344 hydrochloride) is an orally active prodrug of Eglumegad (HY-18941) and a metabotropic glutamate receptor 2/3 (mGluR2/3) agonist. Talaglumetad hydrochloride undergoes transmembrane transport via the intestinal peptide transporter hPepT1, and is enzymatically hydrolyzed to produce L-alanine and the parent drug Eglumegad after entering the body. Talaglumetad hydrochloride can be used in research related to metabotropic glutamate receptor 2-associated neurological systems[1][2].
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Talaglumetad (hydrochloride) | 99.58% | Talaglumetad hydrochloride (LY-544344 hydrochloride) is an orally active prodrug of Eglumegad (HY-18941) and a metabotropic glutamate receptor 2/3 (mGluR2/3) agonist. Talaglumetad hydrochloride undergoes transmembrane transport via the intestinal peptide transporter hPepT1, and is enzymatically hydrolyzed to produce L-alanine and the parent drug Eglumegad after entering the body. Talaglumetad hydrochloride can be used in research related to metabotropic glutamate receptor 2-associated neurological systems. | ||||||||||||||||||||
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