14517-43-2
14517-43-2
Chemical Structure
Methionylserine
Synonym(s): H-MET-SER-OH
- CAS No.: 14517-43-2
- Formula:C8H16N2O4S
- Molecular Weight:236.29
IUPAC Name: L-methionyl-L-serine
InChIKey: WEDDFMCSUNNZJR-WDSKDSINSA-N
SMILES: O=C([C@@H](N)CCSC)N[C@H](C(O)=O)CO
Biological Activity: Methionylserine (H-MET-SER-OH) is a methionine- and serine-containing dipeptide. Methionylserine binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. Methionylserine inhibits ACE enzyme activity. Methionylserine can be used in the research of hypension[1][2].
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Methionylserine | Methionylserine (H-MET-SER-OH) is a methionine- and serine-containing dipeptide. Methionylserine binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. Methionylserine inhibits ACE enzyme activity. Methionylserine can be used in the research of hypension. | |||||||||||||||||||||
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References
- [1]. Diana Højmark Omkvist, et al. Affinity and translocation relationships via hPEPT1 of H-X aa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs. Eur J Pharm Biopharm. 2011 Feb;77(2):327-31. [Content Brief]
- [2]. Pan Wuguang, et al. Application of sulfur dipeptide for preparing antihypertensive drug or health care product. Patent WO2019006954.
