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Cat. No.: HY-170815

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CDK4/9-IN-1

CDK4/9-IN-1 (Compound 29) is a selective dual CDK4/9 inhibitor with IC₅₀ values of 23 nM and 12 nM, respectively. CDK4/9-IN-1 is promising for research of cancers.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2577288-83-4
화학식: C₂₂H₃₄N₆O₂
분자량:414.54

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

CDK4/9-IN-1 Chemical Structure

CAS No.: 2577288-83-4

사이즈

가격

재고

수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

CDK4/9-IN-1 (Compound 29) is a selective dual CDK4/9 inhibitor with IC₅₀ values of 23 nM and 12 nM, respectively. CDK4/9-IN-1 is promising for research of cancers^[1].

IC₅₀ & Target

CDK4

23 nM (IC₅₀)

CDK9

12 nM (IC₅₀)

All CDK Isoforms :

Chemical Information

CAS No. 2577288-83-4
분자량 414.54
화학식 C₂₂H₃₄N₆O₂
SMILES

CN(C)C(C(N(C1CCCC1)C2=N3)=CC2=CN=C3N[C@@H]4CC[C@H](CC4)NCCO)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jiang C, et al. Elucidating Binding Selectivity in Cyclin-Dependent Kinases 4, 6, and 9: Development of Highly Potent and Selective CDK4/9 Inhibitors. J Med Chem. 2025 Jan 23;68(2):1499-1510. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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CDK4/9-IN-1

All CDK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

CDK4/9-IN-1 Related Classifications

HY-170815 Related Classifications