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Cat. No.: HY-142948

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KRAS G12C inhibitor 46

KRAS G12C inhibitor 46 (compound WX003) is a potent KRAS G12C inhibitor.

For research use only. We do not sell to patients.

CAS No.: 2573769-23-8
Formula: C₃₂H₃₃F₂N₇O₂
Molecular Weight:585.65

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

KRAS G12C inhibitor 46 Chemical Structure

CAS No.: 2573769-23-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

KRAS G12C inhibitor 46 (compound WX003) is a potent KRAS G12C inhibitor^[1].

IC₅₀ & Target^[1]

KRas G12C

All Ras Isoforms :

Chemical Information

CAS No. 2573769-23-8
Molecular Weight 585.65
Formula C₃₂H₃₃F₂N₇O₂
SMILES

O=C1N2C3=NC(C4=C(F)C=CC=C4NCCCC5=CC=NC(C(C)C)=C52)=C(F)C=C3C(N6[C@H](CN(CC6)C(C=C)=O)C)=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li Qiu, et al. Macrocyclic compoung serving as Kras inhibitor. WO2021147967A1.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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KRAS G12C inhibitor 46

All Ras Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

KRAS G12C inhibitor 46 Related Classifications

HY-142948 Related Classifications