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Cat. No.: HY-158703

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KRAS G12D inhibitor 24

KRAS G12D inhibitor 24 (compound 103) is a potent inhibitor of KRAS G12D, with the IC₅₀ of 0.004 μM. KRAS G12D inhibitor 24 has oral bioactivity.

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CAS No.: 3033701-29-7
Formule: C₃₄H₃₃F₃N₆O₂
Masse moléculaire:614.66

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

KRAS G12D inhibitor 24 Chemical Structure

CAS No.: 3033701-29-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

KRAS G12D inhibitor 24 (compound 103) is a potent inhibitor of KRAS G12D, with the IC₅₀ of 0.004 μM. KRAS G12D inhibitor 24 has oral bioactivity^[1].

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Chemical Information

CAS No. 3033701-29-7
Masse moléculaire 614.66
Formule C₃₄H₃₃F₃N₆O₂
SMILES

OC1=CC(C2=C(F)C3=NC(OC[C@]4(C)CN(C)CC/C4=C\F)=NC(N5C[C@H](N6)CC[C@H]6C5)=C3C=N2)=C7C(C#C)=C(F)C=CC7=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Tyligand Bioscience (Shanghai) Limited. Quinazoline compounds as KRAS inhibitors and their preparation, pharmaceutical compositions and use in the treatment of cancer. World Intellectual Property Organization, WO2024067714 A1 2024-04-04

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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KRAS G12D inhibitor 24

Voir tous les produits spécifiques à Isoform Ras

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

KRAS G12D inhibitor 24 Related Classifications

HY-158703 Related Classifications